MTL-CEBPA

Generic Name
MTL-CEBPA
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
-
Background

MTL-CEBPA is a SMARTICLES liposomal formulation of MTL-501, a small activating RNA (saRNA) oligonucleotide.

Associated Conditions
-
Associated Therapies
-

Phase I Study of RNA Oligonucleotide, MTL-CEBPA, Atezolizumab and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma.

First Posted Date
2021-10-28
Last Posted Date
2021-10-28
Lead Sponsor
National University Hospital, Singapore
Target Recruit Count
33
Registration Number
NCT05097911
Locations
πŸ‡ΈπŸ‡¬

National University Hospital, Singapore, Singapore

Radomised Phase II Study of MTL-CEBPA Plus Sorafenib or Sorafenib Alone

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2021-01-15
Last Posted Date
2023-11-27
Lead Sponsor
Mina Alpha Limited
Target Recruit Count
150
Registration Number
NCT04710641
Locations
πŸ‡ΊπŸ‡Έ

City of Hope, Duarte, California, United States

πŸ‡ΈπŸ‡¬

National University Hospital Singapore, Singapore, Singapore

A Study of MTL-CEBPA in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumours (TIMEPOINT)

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2019-09-26
Last Posted Date
2023-06-05
Lead Sponsor
Mina Alpha Limited
Target Recruit Count
108
Registration Number
NCT04105335
Locations
πŸ‡¬πŸ‡§

Guys and St Thomas NHS Foundation Trust, London, United Kingdom

πŸ‡¬πŸ‡§

Imperial College Healthcare NHS Trust, London, United Kingdom

πŸ‡¬πŸ‡§

Freeman Hospital, Newcastle Upn Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom

First-in-Human Safety, Tolerability and Antitumour Activity Study of MTL-CEBPA in Patients With Advanced Liver Cancer

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2016-03-22
Last Posted Date
2023-11-27
Lead Sponsor
Mina Alpha Limited
Target Recruit Count
75
Registration Number
NCT02716012
Locations
πŸ‡¨πŸ‡³

National Taiwan University Hospital, Taipei, Taiwan

πŸ‡¬πŸ‡§

University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom

πŸ‡¬πŸ‡§

The Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

and more 8 locations
Β© Copyright 2024. All Rights Reserved by MedPath