Losartan
- Generic Name
- Losartan
- Brand Names
- Hyzaar, Cozaar
- Drug Type
- Small Molecule
- Chemical Formula
- C22H23ClN6O
- CAS Number
- 114798-26-4
- Unique Ingredient Identifier
- JMS50MPO89
- Background
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo or hydrochlorothiazide. Los...
- Indication
Losartan is indicated to treat hypertension in patients older than 6 years, reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy (though this benefit may not extend to patients with African heritage), and to treat diabetic nephropathy with elevated serum creatinine and proteinuria in patients with type 2 diabetes and hyper...
- Associated Conditions
- Diabetic Nephropathy, Ventricular Dysfunction, Hypertension, Marfan Syndrome, Ischemic Stroke
- Associated Therapies
- -
Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia
- Conditions
- Interventions
- First Posted Date
- 2024-12-05
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Hansung University
- Target Recruit Count
- 66
- Registration Number
- NCT06718062
- Locations
- 🇨🇳
Chancheng District People's Hospital, Foshan City, Foshan, Guangdong, China
Losartan and Emotional Processing in Young People
- Conditions
- Interventions
- First Posted Date
- 2024-10-11
- Last Posted Date
- 2024-10-11
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 60
- Registration Number
- NCT06636812
- Locations
- 🇬🇧
Warneford Hospital, University of Oxford, Oxford, Oxfordshire, United Kingdom
Losartan and Emotional Learning
- Conditions
- Interventions
- First Posted Date
- 2024-10-04
- Last Posted Date
- 2024-10-04
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 60
- Registration Number
- NCT06628154
- Locations
- 🇬🇧
Warneford Hospital, University of Oxford, Oxford, Oxfordshire, United Kingdom
Losartan and Social Processing
- Conditions
- Interventions
- First Posted Date
- 2024-10-03
- Last Posted Date
- 2024-10-03
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 58
- Registration Number
- NCT06624904
- Locations
- 🇬🇧
Warneford Hospital, Oxford, Oxfordshire, United Kingdom
Comparison of the Role of Losartan Alone vs Hydrochlorothiazide Plus Losartan
- Conditions
- Interventions
- First Posted Date
- 2024-07-09
- Last Posted Date
- 2024-07-09
- Lead Sponsor
- RESnTEC, Institute of Research
- Target Recruit Count
- 234
- Registration Number
- NCT06491940
- Locations
- 🇵🇰
Medical department, Bahawal Victoria Hospital, Bahawalpur, Punjab, Pakistan
Efficacy and Safety of Telmisartan Compared With Losartan
- Conditions
- Interventions
- First Posted Date
- 2024-05-28
- Last Posted Date
- 2024-05-28
- Lead Sponsor
- Chong Kun Dang Pharmaceutical
- Target Recruit Count
- 98
- Registration Number
- NCT06431477
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.
- First Posted Date
- 2024-04-15
- Last Posted Date
- 2024-06-05
- Lead Sponsor
- University of Kansas Medical Center
- Target Recruit Count
- 42
- Registration Number
- NCT06364176
- Locations
- 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
Losartan Use to Mitigate Arthrofibrosis Following Total Joint Arthroplasty
- First Posted Date
- 2024-03-27
- Last Posted Date
- 2024-03-27
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 240
- Registration Number
- NCT06333522
- Locations
- 🇺🇸
NYU Langone Health, New York, New York, United States
The Effects of Losartan on Attention Control: An Eye-tracking Study
- First Posted Date
- 2024-03-25
- Last Posted Date
- 2024-04-11
- Target Recruit Count
- 80
- Registration Number
- NCT06329050
- Locations
- 🇨🇳
University of Electronic Science and Technology of China, Chengdu, Sichuan, China
Losartan Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study
- First Posted Date
- 2024-03-25
- Last Posted Date
- 2024-04-11
- Target Recruit Count
- 80
- Registration Number
- NCT06329076
- Locations
- 🇨🇳
University of Electronic Science and Technology of China, Chengdu, Sichuan, China
Drug Development Updates
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