Milrinone

Generic Name
Milrinone
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C12H9N3O
CAS Number
78415-72-2
Unique Ingredient Identifier
JU9YAX04C7
Background

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart ...

Indication

Milrinone is indicated for the short-term (48 hours or less) treatment of patients with acute decompensated heart failure. Milrinone administration should occur together with close monitoring using appropriate electrocardiographic equipment and should occur in a facility equipped for the immediate treatment of potential cardiac events, including ventricular ...

Associated Conditions
Acute Decompensated Heart Failure (ADHF), Congestive Heart Failure (CHF)
Associated Therapies
-

Evaluating Precision of Therapy - Milrinone

Phase 2
Completed
Conditions
Interventions
First Posted Date
2013-04-26
Last Posted Date
2022-01-06
Lead Sponsor
The Hospital for Sick Children
Target Recruit Count
52
Registration Number
NCT01841177
Locations
🇨🇦

Hospital for Sick Children, Toronto, Ontario, Canada

🇨🇦

The Hospital for Sick Children, Toronto, Ontario, Canada

Two Inodilators Postsurgery in Neonates

First Posted Date
2012-04-12
Last Posted Date
2012-04-12
Lead Sponsor
Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz
Target Recruit Count
20
Registration Number
NCT01576094
Locations
🇪🇸

Hospital Universitario La Paz, Madrid, Spain

Milrinone During Living Donor Hepatectomy

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2009-08-27
Last Posted Date
2009-08-27
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
38
Registration Number
NCT00966745
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

Milrinone Inhaled in Cardiac Surgery

First Posted Date
2009-01-09
Last Posted Date
2013-10-25
Lead Sponsor
Andre Denault
Target Recruit Count
124
Registration Number
NCT00819377
Locations
🇨🇦

Montreal Heart Institute, Montreal, Quebec, Canada

Levosimendan in Congenital Cardiac Surgery

First Posted Date
2008-06-12
Last Posted Date
2010-01-26
Lead Sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Target Recruit Count
50
Registration Number
NCT00695929
Locations
🇧🇪

Cliniques Universitaires Saint Luc, Brussels, Belgium

Prophylactic Use of Levosimendan Versus Milrinone in Open Heart Surgery in Infants

First Posted Date
2007-10-25
Last Posted Date
2007-10-25
Lead Sponsor
Ludwig Boltzmann Gesellschaft
Target Recruit Count
40
Registration Number
NCT00549107
Locations
🇦🇹

Children´s Heart Center Linz, Linz, Austria

Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery

First Posted Date
2007-10-12
Last Posted Date
2018-06-25
Lead Sponsor
John M Costello
Target Recruit Count
106
Registration Number
NCT00543309
Locations
🇺🇸

Children's Hospital Boston, Boston, Massachusetts, United States

The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG

Phase 3
Completed
Conditions
First Posted Date
2007-03-12
Last Posted Date
2015-06-03
Lead Sponsor
University of Luebeck
Target Recruit Count
60
Registration Number
NCT00446017
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