Vitamin C

Generic Name: Vitamin C

Brand Names: Ascor, Citranatal B-calm Kit, Concept Ob, Ferralet 90, Hematogen, Infuvite, Infuvite Pediatric, Moviprep, Mvc-fluoride, Mvi Pediatric, Natafort, Plenvu, Pregvit, Vitafol-one

Drug Type: Small Molecule

Chemical Formula: C_₆H_₈O_₆

CAS Number: 50-81-7

Unique Ingredient Identifier: PQ6CK8PD0R

Background: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

Indication: Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.

Associated Conditions: Common Cold, Deficiency, Vitamin A, Deficiency, Vitamin D, Fever, Flu caused by Influenza, Folate deficiency, Iron Deficiency (ID), Iron Deficiency Anemia (IDA), Oral bacterial infection, Scurvy, Vitamin C Deficiency, Vitamin Deficiency

Associated Therapies: Nutritional supplementation, Vitamin supplementation

Clinical Trials

Efficacy of Injectable Vitamin C on Accelerating Canine Movement: A Clinical Study

Not Applicable

Completed

Conditions: Palatally Impacted Canines

Interventions: Drug: vitamin C

First Posted Date: 2017-08-24

Last Posted Date: 2017-08-29

Lead Sponsor: Cairo University

Target Recruit Count: 12

Registration Number: NCT03260829

Locations: 🇪🇬
Faculty of Oral and Dental Medicine, Gizah, Giza, Egypt

Use of ARINA-1 in an Intermediate Size Patient Population of Bilateral Lung Transplant Patients With CLAD Grade 0

Phase 1

Completed

Conditions: Lung Transplant

Interventions: Drug: Ascorbic Acid

First Posted Date: 2017-07-21

Last Posted Date: 2019-07-05

Lead Sponsor: Duke University

Target Recruit Count: 6

Registration Number: NCT03226431

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)

Phase 2

Completed

Conditions: Delayed Onset Muscle Soreness, DOMS

Interventions: Drug: Placebo
Drug: Comboprofen
Drug: Magnesium
Drug: Ibuprofen
Drug: Vitamin C

First Posted Date: 2017-07-21

Last Posted Date: 2018-01-23

Lead Sponsor: Spherium Biomed

Target Recruit Count: 74

Registration Number: NCT03223519

Locations: 🇪🇸
Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

Oxidative Stress Expression and Metabolic Imbalance in Critically Ill Polytrauma Patients and the Implications of Antioxidant Therapy on Clinical Outcomes

Not Applicable

Conditions: Oxidative Stress
Polytrauma

Interventions: Drug: Vitamin C

First Posted Date: 2017-07-14

Last Posted Date: 2019-03-07

Lead Sponsor: Romanian Society of Anesthesia and Intensive Care

Target Recruit Count: 100

Registration Number: NCT03218280

Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer

Phase 1

Conditions: Breast Cancer

Interventions: Drug: Placebos
Drug: Ascorbic Acid

First Posted Date: 2017-06-05

Last Posted Date: 2018-06-27

Lead Sponsor: Academic Emergency County Hospital Sibiu

Target Recruit Count: 30

Registration Number: NCT03175341

Locations: 🇷🇴
Academic Emergency County Hospital Sibiu, Sibiu, Romania

Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function

Phase 1

Terminated

Conditions: Smoking
Endothelial Dysfunction

Interventions: Other: Charcoal hookah
Drug: Carbon Monoxide inhalation
Drug: vitamin C
Other: E-coal hookah
Other: Room Air inhalation
Drug: tadalafil
Other: Cigarette

First Posted Date: 2017-05-25

Last Posted Date: 2021-04-09

Lead Sponsor: Cedars-Sinai Medical Center

Target Recruit Count: 60

Registration Number: NCT03166787

Locations: 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States

High Dose Vitamin C Intravenous Infusion in Patients With Resectable or Metastatic Solid Tumor Malignancies

Phase 2

Completed

Conditions: Colorectal Cancer
Pancreatic Cancer
Lung Cancer

Interventions: Drug: Vitamin C

First Posted Date: 2017-05-10

Last Posted Date: 2024-05-02

Lead Sponsor: Weill Medical College of Cornell University

Target Recruit Count: 61

Registration Number: NCT03146962

Locations: 🇺🇸
Weill Cornell Medical College, New York, New York, United States
🇺🇸
New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York, United States

Vitamin C in Atrial Fibrillation Ablation

Phase 2

Completed

Conditions: Atrial Fibrillation Ablation

Interventions: Drug: Vitamin C
Other: Placebo

First Posted Date: 2017-05-10

Last Posted Date: 2019-04-16

Lead Sponsor: Virginia Commonwealth University

Target Recruit Count: 20

Registration Number: NCT03148236

Locations: 🇺🇸
Virginia Commonwealth University, Richmond, Virginia, United States

Vitamin C in Cardiac Surgery Patients

Phase 1

Completed

Conditions: Coronary Artery Bypass Graft Surgery

Interventions: Drug: Ascorbic Acid

First Posted Date: 2017-04-21

Last Posted Date: 2021-06-16

Lead Sponsor: Geisinger Clinic

Target Recruit Count: 6

Registration Number: NCT03123107

Locations: 🇺🇸
Geisinger Wyoming Valley Medical Center, Wilkes-Barre, Pennsylvania, United States

Delivery of Inhibitors of Lysyl Oxidase (LysoLox) on Serial Angioplasty and Time to Restenosis

Phase 2

Conditions: Arteriovenous Fistula Occlusion

Interventions: Drug: Cuprimine Oral Product
Drug: Placebo
Drug: Ascorbic Acid

First Posted Date: 2017-04-11

Last Posted Date: 2017-09-11

Lead Sponsor: Southeast Renal Research Institute

Target Recruit Count: 30

Registration Number: NCT03106948

Locations: 🇺🇸
Southeast Renal Research Institute, Chattanooga, Tennessee, United States

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