Vitamin C
- Generic Name
- Vitamin C
- Brand Names
- Ascor, Citranatal B-calm Kit, Concept Ob, Ferralet 90, Hematogen, Infuvite, Infuvite Pediatric, Moviprep, Mvc-fluoride, Mvi Pediatric, Natafort, Plenvu, Pregvit, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C6H8O6
- CAS Number
- 50-81-7
- Unique Ingredient Identifier
- PQ6CK8PD0R
- Background
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxi...
- Indication
Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
- Associated Conditions
- Common Cold, Deficiency, Vitamin A, Deficiency, Vitamin D, Fever, Flu caused by Influenza, Folate deficiency, Iron Deficiency (ID), Iron Deficiency Anemia (IDA), Oral bacterial infection, Scurvy, Vitamin C Deficiency, Vitamin Deficiency
- Associated Therapies
- Nutritional supplementation, Vitamin supplementation
Alcohol Abuse or Alcohol Withdrawal: Risk of Latent Scurvy
- Conditions
- First Posted Date
- 2018-03-15
- Last Posted Date
- 2018-03-26
- Lead Sponsor
- SCP Battistelli
- Target Recruit Count
- 47
- Registration Number
- NCT03467022
Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia
- Conditions
- Interventions
- First Posted Date
- 2018-03-01
- Last Posted Date
- 2019-06-28
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 34
- Registration Number
- NCT03451266
- Locations
- 🇸🇮
UMC Ljubljana, Ljubljana, Slovenia
A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations
- First Posted Date
- 2018-02-15
- Last Posted Date
- 2024-03-27
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 4
- Registration Number
- NCT03433781
- Locations
- 🇺🇸
University of Miami Miller School of Medicine -Sylvester Cancer Center, Miami, Florida, United States
🇺🇸New York University School of Medicine, New York, New York, United States
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
- Conditions
- Interventions
- First Posted Date
- 2018-02-05
- Last Posted Date
- 2021-09-21
- Lead Sponsor
- Community Medical Center, Toms River, NJ
- Target Recruit Count
- 140
- Registration Number
- NCT03422159
- Locations
- 🇺🇸
Community Medical Center, Toms River, New Jersey, United States
🇺🇸Monmouth Medical Center, Southern Campus, Lakewood, New Jersey, United States
Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM)
- First Posted Date
- 2018-01-25
- Last Posted Date
- 2023-04-18
- Lead Sponsor
- HonorHealth Research Institute
- Target Recruit Count
- 27
- Registration Number
- NCT03410030
- Locations
- 🇺🇸
HonorHealth Research Institute, Scottsdale, Arizona, United States
TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid
- Conditions
- Interventions
- First Posted Date
- 2018-01-11
- Last Posted Date
- 2021-08-11
- Lead Sponsor
- Case Comprehensive Cancer Center
- Target Recruit Count
- 12
- Registration Number
- NCT03397173
- Locations
- 🇺🇸
Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
Vitamin C and Septic Shock
- First Posted Date
- 2017-11-09
- Last Posted Date
- 2021-07-14
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 125
- Registration Number
- NCT03338569
- Locations
- 🇺🇸
University of Minnesota Medical Center, Minneapolis, Minnesota, United States
Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery
- First Posted Date
- 2017-11-07
- Last Posted Date
- 2022-03-31
- Lead Sponsor
- Academic and Community Cancer Research United
- Target Recruit Count
- 5
- Registration Number
- NCT03334409
- Locations
- 🇺🇸
Carle Cancer Center, Urbana, Illinois, United States
🇺🇸Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota, United States
🇺🇸Sanford Medical Center Fargo, Fargo, North Dakota, United States
The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock
- Conditions
- Interventions
- First Posted Date
- 2017-11-07
- Last Posted Date
- 2019-02-19
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 5
- Registration Number
- NCT03335124
- Locations
- 🇸🇮
Department of Gastroenterology, UMC Ljubljana, Ljubljana, Slovenia
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial
- Conditions
- Interventions
- First Posted Date
- 2017-11-06
- Last Posted Date
- 2019-10-10
- Target Recruit Count
- 216
- Registration Number
- NCT03333278
- Locations
- 🇦🇺
Alfred Hospital, Melbourne, Victoria, Australia
🇦🇺Royal Melbourne Hospital, Melbourne, Victoria, Australia
🇦🇺Austin Health, Heidelberg, Victoria, Australia
Drug Development Updates
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