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Pemetrexed

Generic Name
Pemetrexed
Brand Names
Alimta, Ciambra, Pemfexy, Pemrydi Rtu, Pemetrexed Fresenius Kabi, Pemetrexed Baxter, Pemetrexed Krka, Pemetrexed medac, Pemetrexed Accord, Pemetrexed Sandoz, Armisarte (previously Pemetrexed Actavis)
Drug Type
Small Molecule
Chemical Formula
C20H21N5O6
CAS Number
137281-23-3
Unique Ingredient Identifier
04Q9AIZ7NO

Overview

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery. Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.

Background

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery. Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.

Indication

Pemetrexed is indicated for the treatment of the following conditions: Non-squamous non-small cell lung cancer (NSCLC) Malignant pleural mesothelioma

Associated Conditions

  • Metastatic Cervical Cancer
  • Metastatic Non-squamous Non Small Cell Lung Cancer
  • Metastatic Urothelial Carcinoma (UC)
  • Ovarian Cancer
  • Locally advanced nonsquamous non-small cell lung cancer
  • Recurrent, metastatic Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)
  • Unresectable Malignant Pleural Mesothelioma (MPM)
  • Unresectable Thymoma

FDA Approved Products

Pemetrexed
Manufacturer:BluePoint Laboratories
Route:INTRAVENOUS
Strength:100 mg in 4 mL
Approved: 2023/10/10
NDC:68001-543
Pemetrexed
Manufacturer:Sandoz Inc.
Route:INTRAVENOUS
Strength:500 mg in 20 mL
Approved: 2022/05/25
NDC:0781-3519
Pemetrexed
Manufacturer:Apotex Corp
Route:INTRAVENOUS
Strength:1000 mg in 40 mL
Approved: 2024/01/04
NDC:60505-6067
Pemetrexed
Manufacturer:Meitheal Pharmaceuticals Inc.
Route:INTRAVENOUS
Strength:500 mg in 20 mL
Approved: 2022/11/15
NDC:71288-146
Pemetrexed
Manufacturer:Meitheal Pharmaceuticals Inc.
Route:INTRAVENOUS
Strength:100 mg in 4.2 mL
Approved: 2022/11/15
NDC:71288-145

Singapore Approved Products

No Singapore products found for this drug

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