Overview
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate. Triamcinolone was granted FDA approval on 3 December 1957. In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval - for the treatment of patients with macular edema associated with uveitis.
Background
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate. Triamcinolone was granted FDA approval on 3 December 1957. In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval - for the treatment of patients with macular edema associated with uveitis.
Indication
肾上腺皮质激素类药。主要用于过敏性与自身免疫性炎症性疾病。由于本品潴钠作用较弱，故一般不用作肾上腺皮质功能减退的替代治疗。
Associated Conditions
- Acne
- Acne Vulgaris
- Acute Gouty Arthritis
- Allergic Contact Dermatitis
- Allergic Rhinitis (AR)
- Allergic Skin Reaction
- Alopecia Areata (AA)
- Ankylosing Spondylitis (AS)
- Aphthous Stomatitis
- Asthma
- Atopic Dermatitis
- Autoimmune Hemolytic Anemia
- Berylliosis
- Bullous dermatitis herpetiformis
- Chronic Eczema
- Chronic Inflammatory Skin Diseases
- Congenital Adrenal Hyperplasia (CAH)
- Congenital Hypoplastic Anemia
- Contact Dermatitis
- Crohn's Disease (CD)
- Dental Cavity
- Dermatitis
- Dermatomyositis (DM)
- Diaper Rash
- Discoid Lupus Erythematosus (DLE)
- Edema of the cerebrum
- Epicondylitis
- Erythroderma
- Fungal Infections
- Fungal infectious disorders of the Beard
- Fungal skin infection
- Gingivitis
- Haemorrhoids
- Hemangiomas
- Hypercalcemia
- Inflammation of Mouth
- Intertrigo
- Itching of the Anus
- Itching of the External Genitalia
- Itching of the Foot
- Itching of the genitals
- Itching of the hand
- Juvenile Idiopathic Arthritis (JIA)
- Keloids Scars
- Leukemias
- Lichen Planus (LP)
- Lichen simplex chronicus
- Lymphoma
- Macular Edema
- Mycosis Fungoides (MF)
- Mycotic Eczema
- Necrobiosis lipoidica diabeticorum
- Neurodermatitis
- Nummular Dermatitis
- Ocular Inflammation
- Ophthalmia, Sympathetic
- Oral Erosive Lichen Planus
- Otitis Externa
- Pemphigus
- Pericarditis
- Polymyositis
- Postherpetic Neuralgia
- Primary adrenocortical insufficiency
- Proteinuria
- Psoriasis Vulgaris (Plaque Psoriasis)
- Psoriatic Arthritis
- Psoriatic plaque
- Pure Red Cell Aplasia
- Purulent Wounds
- Pyoderma caused by susceptible bacteria
- Regional Enteritis
- Rheumatoid Arthritis
- Ringworm Folliculitis
- Seborrheic Dermatitis
- Seborrheic Dermatitis, Eczematous
- Secondary Impetiginization
- Secondary adrenocortical insufficiency
- Secondary thrombocytopenia
- Serum Sickness
- Skin chapped
- Stomatitis, Denture
- Synovitis
- Systemic Lupus Erythematosus
- Temporal Arteritis
- Tinea Corporis
- Transfusion Reactions
- Trichinosis
- Tuberculosis (TB)
- Ulcerative Colitis
- Urticaria
- Uveitis
- Wound Infections
- Acute Bursitis
- Acute Multiple sclerosis
- Acute Rheumatic heart disease, unspecified
- Acute Tenosynovitis
- Corticosteroid-responsive dermatoses
- Cutaneous candidiasis
- Cystic tumour of the ganglia
- Exfoliative erythroderma
- Granuloma annulare lesions
- Idiopathic eosinophilic pneumonias
- Non-suppurative Thyroiditis
- Oral infections
- Oral lesions
- Severe Erythema multiforme
- Subacute Dermatitis, Eczematous
- Symptomatic Sarcoidosis
- Ulceration of the mouth
- Ulcerative stomatitis
Clinical Trials
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Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2021/05/13 | Phase 2 | Active, not recruiting | |||
2021/04/28 | Phase 1 | UNKNOWN | Fundación Oftalmológica de Santander Clínica Carlos Ardila Lulle | ||
2021/04/12 | N/A | Completed | |||
2021/04/06 | Not Applicable | Completed | Şeyhmus KAPLAN | ||
2021/04/05 | Phase 1 | Terminated | |||
2021/04/01 | Not Applicable | Completed | |||
2021/02/09 | Phase 2 | Recruiting | |||
2021/02/09 | Phase 2 | UNKNOWN | |||
2021/01/29 | Phase 4 | Terminated | |||
2021/01/15 | Not Applicable | Completed | Our Lady of the Lake Hospital |
FDA Drug Approvals
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Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Target Corporation | 11673-717 | NASAL | 55 ug in 1 1 | 4/29/2025 | |
| Dispensing Solutions, Inc. | 68258-8903 | INTRA-ARTICULAR, INTRALESIONAL | 10 mg in 1 mL | 6/14/2013 | |
| NuCare Pharmaceuticals,Inc. | 68071-4383 | TOPICAL | 1 mg in 1 g | 2/16/2021 | |
| Encube Ethicals Private Limited | 21922-024 | TOPICAL | 0.5 mg in 1 g | 1/5/2024 | |
| Taro Pharmaceuticals U.S.A., Inc. | 51672-1272 | TOPICAL | 1 mg in 1 g | 12/11/2019 | |
| Novel Laboratories, Inc. | 40032-097 | TOPICAL | 1 mg in 1 g | 11/28/2018 | |
| NuCare Pharmaceuticals,Inc. | 66267-933 | TOPICAL | 1 mg in 1 g | 1/11/2021 | |
| NuCare Pharmaceuticals,Inc. | 68071-2743 | TOPICAL | 1 mg in 1 g | 6/2/2022 | |
| E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. | 0168-0089 | TOPICAL | 1 mg in 1 g | 11/29/2018 | |
| Preferred Pharmaceuticals, Inc. | 68788-8386 | TOPICAL | 1 mg in 1 g | 3/1/2023 |
EMA Drug Approvals
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Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
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|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
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|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
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Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
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Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
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| No TGA approvals found for this drug. | |||||