Triamcinolone

Generic Name: Triamcinolone

Brand Names: Allernaze, Aristocort, Aristocort R, Juulissa Pharmapak, Kenalog, Kourzeq, Marcaine, Nasacort, Oracort, Oralone, Pediaderm Ta, Triaderm, Trianex, Triderm, Triesence, Triloan Suik, Tritocin, Viaderm Kc, Xipere, Zilretta

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₇FO_₆

CAS Number: 124-94-7

Unique Ingredient Identifier: 1ZK20VI6TY

Background: Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.

Triamcinolone was granted FDA approval on 3 December 1957. In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval - for the treatment of patients with macular edema associated with uveitis.

Indication: 肾上腺皮质激素类药。主要用于过敏性与自身免疫性炎症性疾病。由于本品潴钠作用较弱，故一般不用作肾上腺皮质功能减退的替代治疗。

Associated Conditions: Acne, Acne Vulgaris, Acute Gouty Arthritis, Allergic Contact Dermatitis, Allergic Rhinitis (AR), Allergic Skin Reaction, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Aphthous Stomatitis, Asthma, Atopic Dermatitis, Autoimmune Hemolytic Anemia, Berylliosis, Bullous dermatitis herpetiformis, Chronic Eczema, Chronic Inflammatory Skin Diseases, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Crohn's Disease (CD), Dental Cavity, Dermatitis, Dermatomyositis (DM), Diaper Rash, Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Erythroderma, Fungal Infections, Fungal infectious disorders of the Beard, Fungal skin infection, Gingivitis, Haemorrhoids, Hemangiomas, Hypercalcemia, Inflammation of Mouth, Intertrigo, Itching of the Anus, Itching of the External Genitalia, Itching of the Foot, Itching of the genitals, Itching of the hand, Juvenile Idiopathic Arthritis (JIA), Keloids Scars, Leukemias, Lichen Planus (LP), Lichen simplex chronicus, Lymphoma, Macular Edema, Mycosis Fungoides (MF), Mycotic Eczema, Necrobiosis lipoidica diabeticorum, Neurodermatitis, Nummular Dermatitis, Ocular Inflammation, Ophthalmia, Sympathetic, Oral Erosive Lichen Planus, Otitis Externa, Pemphigus, Pericarditis, Polymyositis, Postherpetic Neuralgia, Primary adrenocortical insufficiency, Proteinuria, Psoriasis Vulgaris (Plaque Psoriasis), Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Purulent Wounds, Pyoderma caused by susceptible bacteria, Regional Enteritis, Rheumatoid Arthritis, Ringworm Folliculitis, Seborrheic Dermatitis, Seborrheic Dermatitis, Eczematous, Secondary Impetiginization, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Skin chapped, Stomatitis, Denture, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Tinea Corporis, Transfusion Reactions, Trichinosis, Tuberculosis (TB), Ulcerative Colitis, Urticaria, Uveitis, Wound Infections, Acute Bursitis, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute Tenosynovitis, Corticosteroid-responsive dermatoses, Cutaneous candidiasis, Cystic tumour of the ganglia, Exfoliative erythroderma, Granuloma annulare lesions, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Oral infections, Oral lesions, Severe Erythema multiforme, Subacute Dermatitis, Eczematous, Symptomatic Sarcoidosis, Ulceration of the mouth, Ulcerative stomatitis

Associated Therapies: -

Clinical Trials

Ketorolac Versus Triamcinolone Knee Injections for Osteoarthritis

Not Applicable

Completed

Conditions: Knee Osteoarthritis

Interventions: Drug: Ketorolac Tromethamine
Drug: Triamcinolone Acetonide

First Posted Date: 2014-11-20

Last Posted Date: 2014-11-20

Lead Sponsor: San Antonio Military Medical Center

Target Recruit Count: 36

Registration Number: NCT02295189

Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide

Phase 1

Completed

Conditions: CYSTOID MACULAR EDEMA

Interventions: Drug: Ranibizumab,
Drug: Triamcinolone acetonide

First Posted Date: 2014-11-19

Last Posted Date: 2018-09-11

Lead Sponsor: Soll Eye

Target Recruit Count: 4

Registration Number: NCT02294656

Locations: 🇺🇸
Soll Eye, Philadelphia, Pennsylvania, United States

Cytokine Levels in Patients With Persistent Diabetic Macular Edema Treated With Triamcinolone Acetonide

Phase 2

Completed

Conditions: Diabetic Macular Edema

Interventions: Drug: Triamcinolone Acetonide

First Posted Date: 2014-08-20

Last Posted Date: 2019-09-19

Lead Sponsor: Unity Health Toronto

Target Recruit Count: 3

Registration Number: NCT02221453

Locations: 🇨🇦
St. Michael's Hospital Eye Clinic, Toronto, Ontario, Canada

Assessing the Efficacy of Needling With or Without Corticosteroids in the Repigmentation of Vitiligo

Phase 2

Terminated

Conditions: Vitiligo

Interventions: Procedure: Needling
Drug: Triamcinolone

First Posted Date: 2014-07-16

Last Posted Date: 2017-07-25

Lead Sponsor: Rutgers, The State University of New Jersey

Target Recruit Count: 22

Registration Number: NCT02191748

Locations: 🇺🇸
RWJUH Dermatology office, Somerset, New Jersey, United States

Treatment of Keloidscars With Intralesional Triamcinolone and 5-fluorouracil Injections-prospective, Randomized, Controlled Trial - Pilot Study

Phase 4

Completed

Conditions: Keloidscars

Interventions: Drug: Triamcinolone
Drug: 5-fluorouracil

First Posted Date: 2014-06-04

Last Posted Date: 2018-04-26

Lead Sponsor: Tampere University Hospital

Target Recruit Count: 50

Registration Number: NCT02155439

Locations: 🇫🇮
Tampere university hospital, Tampere, Finland

Using Saline for Myofascial Pain Syndromes (USAMPS)

Phase 4

Terminated

Conditions: Myofascial Pain Syndrome

Interventions: Drug: Normal Saline
Drug: Lidocaine Hydrochloride
Drug: Triamcinolone acetonide

First Posted Date: 2014-04-22

Last Posted Date: 2019-05-01

Lead Sponsor: The University of Texas Health Science Center, Houston

Target Recruit Count: 51

Registration Number: NCT02120261

Locations: 🇺🇸
Memorial Hermann Hospital Texas Medical Center, Houston, Texas, United States
🇺🇸
Lyndon Baines Johnson General Hospital, Houston, Texas, United States