MedPath

CDR-132L

Generic Name
CDR-132L

A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy

Phase 2
Not yet recruiting
Conditions
Heart Failure
Interventions
Drug: Placebo
First Posted Date
2025-05-19
Last Posted Date
2025-05-19
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
200
Registration Number
NCT06979375
Locations
🇦🇺

Victorian Heart Hospital, Clayton, Victoria, Australia

🇦🇺

Fiona Stanley Hospital Cardiology, Murdoch, Western Australia, Australia

🇨🇿

Fakultní nemocnice u sv. Anny v Brně, Brno, Czechia

and more 72 locations

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

Phase 2
Not yet recruiting
Conditions
Heart Failure
Interventions
Drug: Placebo
First Posted Date
2025-05-19
Last Posted Date
2025-05-19
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
200
Registration Number
NCT06979362
Locations
🇮🇳

Sengupta Hospital and Research Institute, Nagpur, Maharashtra, India

🇺🇸

Duke University_Durham, Durham, North Carolina, United States

🇺🇸

Univ of Alabama Birmingham, Birmingham, Alabama, United States

and more 80 locations

Reverse Remodeling Effects of CDR132L in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Cardiac Hypertrophy

Phase 2
Withdrawn
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
Drug: Placebo
First Posted Date
2023-07-20
Last Posted Date
2024-06-05
Lead Sponsor
Cardior Pharmaceuticals GmbH
Registration Number
NCT05953831

Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction

Phase 2
Completed
Conditions
Myocardial Infarction, Acute
Heart Failure, Left Sided
Interventions
Drug: Placebo to CDR132L
First Posted Date
2022-04-28
Last Posted Date
2025-04-03
Lead Sponsor
Cardior Pharmaceuticals GmbH
Target Recruit Count
294
Registration Number
NCT05350969
Locations
🇵🇱

Polsko Amerykanskie Kliniki Serca, Kędzierzyn-Koźle, Poland

🇵🇱

NZOZ Pro-Cordis Sopockie Centrum Bad. Kardiolog, Sopot, Poland

🇳🇱

Deventer Ziekenhuis, Deventer, Netherlands

and more 51 locations

Clinical Study to Assess Safety, PK and PD Parameters of CDR132L

Phase 1
Completed
Conditions
Heart Failure
Interventions
First Posted Date
2019-08-05
Last Posted Date
2022-03-09
Lead Sponsor
Cardior Pharmaceuticals GmbH
Target Recruit Count
28
Registration Number
NCT04045405
Locations
🇬🇧

Richmond Pharmacology Ltd., 1A Newcomen Street, London Bridge, London, United Kingdom

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