Nabilone

Generic Name
Nabilone
Brand Names
Cesamet
Drug Type
Small Molecule
Chemical Formula
C24H36O3
CAS Number
51022-71-0
Unique Ingredient Identifier
2N4O9L084N
Background

Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however...

Indication

Nabilone is indicated for the treatment of the nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments. This restriction is required because a substantial proportion of any group of patients treated with Nabilone can be expected to experience disturbing psychotomimetic re...

Associated Conditions
Refractory Chemotherapy-Induced Nausea and Vomiting (CINV)
Associated Therapies
-

A Trial Assessing the Effect of Nabilone on Pain and Quality of Life in Patients With Fibromyalgia

Phase 2
Completed
Conditions
First Posted Date
2006-01-04
Last Posted Date
2011-08-25
Lead Sponsor
Winnipeg Regional Health Authority
Target Recruit Count
40
Registration Number
NCT00272207
Locations
🇨🇦

Rehabilitation Hospital, Winnipeg, Manitoba, Canada

© Copyright 2024. All Rights Reserved by MedPath