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Rabies immune globulin, human is a solution of antibodies used to prevent rabies after an exposure.
Rabies immune globulin, human is a solution of antibodies used to prevent rabies after an exposure.
Rabies immune globulin binds the rabies virus, preventing it from invading the central nervous system . This affords time for the rabies vaccine, which is also administered in cases of rabies exposure, to induce an immune response to destroy the virus. Rabies immunoglobulin should only be administered up to eight days after exposure as the host begins to produce sufficient antibodies to the virus one week after exposure. Repeat dosing should also be avoided as it may interfere with induction of immune response by the rabies vaccine.
The human rabies immune globulin is used indicated for passive, transient post-exposure prophylaxis of rabies infection to persons of all ages when given immediately after contact with a rabid or possibly rabid animal. It should be administered concurrently with a full course of rabies vaccine.
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