Luliconazole
- Generic Name
- Luliconazole
- Brand Names
- Luzu
- Drug Type
- Small Molecule
- Chemical Formula
- C14H9Cl2N3S2
- CAS Number
- 187164-19-8
- Unique Ingredient Identifier
- RE91AN4S8G
- Background
Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan.
- Indication
Luliconazole is indicated for the treatment of interdigital tinea pedis, tinea cruris, or tinea corporis infections caused by Trichophyton rubrum and Epidermophyton floccosum.
- Associated Conditions
- Tinea infections of the feet caused by Epidermophyton floccosum, Tinea infections of the feet caused by Trichophyton rubrum
Safety and Efficacy of Product 33525 (Luliconazole Cream 1%) in Pediatric Participants With Tinea Corporis
- First Posted Date
- 2016-05-11
- Last Posted Date
- 2019-11-27
- Lead Sponsor
- Bausch Health Americas, Inc.
- Target Recruit Count
- 75
- Registration Number
- NCT02767947
- Locations
- π©π΄
Valeant Site 01, Santo Domingo, Dominican Republic
ππ³Valeant Site 02, San Pedro Sula, Honduras
π©π΄Valeant Site 03, San Cristobal, Dominican Republic
Maximal Use of Luliconazole Cream 1% in Pediatric Participants With Moderate to Severe Tinea Pedis or Tinea Cruris
- First Posted Date
- 2016-05-10
- Last Posted Date
- 2019-11-27
- Lead Sponsor
- Bausch Health Americas, Inc.
- Target Recruit Count
- 30
- Registration Number
- NCT02767271
- Locations
- ππ³
Valeant Site 02, San Pedro Sula, Honduras
π©π΄Valeant Site 01, Santo Domingo, Dominican Republic
Study Evaluating the Drug Interaction Potential of Luliconazole Cream 1% in Participants With Tinea Pedis and Tinea Cruris
- Conditions
- Tinea CrurisTinea Pedis
- Interventions
- First Posted Date
- 2015-03-20
- Last Posted Date
- 2019-11-27
- Lead Sponsor
- Bausch & Lomb Incorporated
- Target Recruit Count
- 20
- Registration Number
- NCT02394340
- Locations
- πΊπΈ
TKL Research, Fair Lawn, New Jersey, United States
Safety and Efficacy of Luliconazole Solution, 10% in Subjects With Mild to Moderate Onychomycosis
- Conditions
- Distal and Lateral Subungual Onychomycosis
- Interventions
- Drug: Vehicle Solution
- First Posted Date
- 2011-09-12
- Last Posted Date
- 2015-11-30
- Lead Sponsor
- Topica Pharmaceuticals
- Target Recruit Count
- 334
- Registration Number
- NCT01431820
Topical Antifungal Treatment for Tinea Pedis
- First Posted Date
- 2011-07-19
- Last Posted Date
- 2013-08-28
- Lead Sponsor
- Medicis Global Service Corporation
- Target Recruit Count
- 321
- Registration Number
- NCT01396785
Topical Antifungal Treatment for Tinea Pedis
- First Posted Date
- 2011-07-19
- Last Posted Date
- 2013-08-28
- Lead Sponsor
- Medicis Global Service Corporation
- Target Recruit Count
- 322
- Registration Number
- NCT01396811
Topical Antifungal Treatment for Tinea Cruris
- First Posted Date
- 2011-04-27
- Last Posted Date
- 2013-08-28
- Lead Sponsor
- Medicis Global Service Corporation
- Target Recruit Count
- 483
- Registration Number
- NCT01342315
Open-Label Pharmacokinetics (PK)/Safety Study of Luliconazole Solution, 10% in Distal Subungual Onychomycosis
- First Posted Date
- 2010-01-07
- Last Posted Date
- 2014-11-26
- Lead Sponsor
- Topica Pharmaceuticals
- Target Recruit Count
- 24
- Registration Number
- NCT01044381
- Locations
- πΊπΈ
J&S Studies, College Station, Texas, United States
Multicenter Study of the Efficacy and Safety of Luliconazole Cream in Tinea Pedis (Athlete's Foot)
- Conditions
- Tinea Pedis
- Interventions
- Drug: Placebo Comparator -2 wksDrug: Placebo Comparator - 4 wks
- First Posted Date
- 2009-03-26
- Last Posted Date
- 2011-06-21
- Lead Sponsor
- Tinea Pharmaceuticals
- Target Recruit Count
- 147
- Registration Number
- NCT00869336
Drug Development Updates
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