Coenzyme M
- Generic Name
- Coenzyme M
- Brand Names
- Uromitexan
- Drug Type
- Small Molecule
- Chemical Formula
- C2H6O3S2
- CAS Number
- 3375-50-6
- Unique Ingredient Identifier
- VHD28S0H7F
- Background
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
- Indication
Mesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
- Associated Conditions
- Hemorrhagic cystitis caused by cyclophosphamide, Hemorrhagic cystitis caused by ifosfamide
- Associated Therapies
- -
Haploidentical Natural Killer (NK) Cells in Patients With Relapsed or Refractory Neuroblastoma
- Conditions
- Interventions
- First Posted Date
- 2008-06-16
- Last Posted Date
- 2020-09-24
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 1
- Registration Number
- NCT00698009
- Locations
- 🇺🇸
UT MD Anderson Cancer Center, Houston, Texas, United States
Autologous Stem Cell Transplantation for Crohn's Disease
- First Posted Date
- 2008-06-06
- Last Posted Date
- 2024-02-14
- Lead Sponsor
- Paul Szabolcs
- Target Recruit Count
- 20
- Registration Number
- NCT00692939
- Locations
- 🇺🇸
UPMC Prebyterian- Adult Gastroenterology, Pittsburgh, Pennsylvania, United States
🇺🇸Children's Hospital of Pittsburgh of UPMC-Bone Marrow Team, Pittsburgh, Pennsylvania, United States
Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy
- First Posted Date
- 2008-05-07
- Last Posted Date
- 2014-09-10
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 7
- Registration Number
- NCT00673179
- Locations
- 🇺🇸
UT MD Anderson Cancer Center, Houston, Texas, United States
Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia
- First Posted Date
- 2008-05-05
- Last Posted Date
- 2020-12-03
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 220
- Registration Number
- NCT00671658
- Locations
- 🇺🇸
UT MD Anderson Cancer Center, Houston, Texas, United States
Autologous Bone Marrow Transplant for Children With Acute Myelogenous Leukemia (AML) in First Complete Remission
- Conditions
- Interventions
- First Posted Date
- 2008-04-28
- Last Posted Date
- 2008-04-28
- Lead Sponsor
- St. Jude Children's Research Hospital
- Target Recruit Count
- 17
- Registration Number
- NCT00667927
- Locations
- 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
MT2004-30: Tomotherapy for Solid Tumors
- Conditions
- Interventions
- First Posted Date
- 2008-02-25
- Last Posted Date
- 2017-12-05
- Lead Sponsor
- Masonic Cancer Center, University of Minnesota
- Target Recruit Count
- 23
- Registration Number
- NCT00623077
- Locations
- 🇺🇸
Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States
T-Regulatory Cell Kinetics, Stem Cell Transplantation, REGKINE
- Conditions
- Interventions
- First Posted Date
- 2007-12-21
- Last Posted Date
- 2016-04-22
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 26
- Registration Number
- NCT00578461
- Locations
- 🇺🇸
Texas Children's Hospital, Houston, Texas, United States
Protracted Etoposide During Induction Therapy for High Risk Neuroblastoma
- First Posted Date
- 2007-12-21
- Last Posted Date
- 2020-03-27
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 13
- Registration Number
- NCT00578864
- Locations
- 🇺🇸
Texas Children's Hospital, Houston, Texas, United States
Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO
- Conditions
- Interventions
- First Posted Date
- 2007-12-21
- Last Posted Date
- 2020-05-01
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 10
- Registration Number
- NCT00578292
- Locations
- 🇺🇸
Texas Children's Hospital, Houston, Texas, United States
T-Reg Cell Kinetics, Stem Cell Transplant, REGALE
- First Posted Date
- 2007-12-21
- Last Posted Date
- 2016-04-22
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 24
- Registration Number
- NCT00578539
- Locations
- 🇺🇸
Texas Children's Hospital, Houston, Texas, United States
Drug Development Updates
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