Pyridoxine

Generic Name
Pyridoxine
Brand Names
Alertonic, Animi-3 With Vitamin D, Bonjesta, Citranatal B-calm Kit, Citranatal Harmony, Concept Ob, Diclectin, Diclegis, Folbic, Foltabs, Fortaplex, Infuvite, Infuvite Pediatric, Irospan 24/6 Kit, Isotamine B, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Pregvit, Tandem Plus, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
C8H11NO3
CAS Number
65-23-6
Unique Ingredient Identifier
KV2JZ1BI6Z
Background

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are able to synthesize pyr...

Indication

Pyridoxine is indicated for the treatment of vitamin B6 deficiency and for the prophylaxis of Isoniazid-induced peripheral neuropathy. It is also approved by Health Canada for the treatment of nausea and vomiting in pregnancy in a combination product with Doxylamine (as the commercially available product Diclectin).

Associated Conditions
Back pain, Dizziness, Fever, Headache, Hepatic; Functional Disturbance, Hepatitis, Iron Deficiency Anemia (IDA), Ketosis, Macrocytic anemia, Menière's Disease, Menstrual Distress (Dysmenorrhea), Metabolic Acidosis, Motion Sickness, Myalgia, Nausea and vomiting, Neuralgia, Sciatic, Neuritis, Neurological Conditions caused by B Vitamin Deficiency, Secondary anemia, Toothache, Toxinfectious state, Trigeminal Neuralgia (TN), Vitamin B1 deficiency, Vitamin B12 Deficiency, Vitamin B6 Deficiency, Vitamin Deficiency, Minor aches and pains, Minor pain
Associated Therapies
Nutritional supplementation, Supplementation, Vitamin supplementation, Wellness of the Liver
Clinical Trials
Related News

The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other Antiemetics

First Posted Date
2024-04-30
Last Posted Date
2024-04-30
Lead Sponsor
University of Baghdad
Target Recruit Count
250
Registration Number
NCT06390787
Locations
🇮🇶

Al-Nassiryah Teaching Hospital, Nasiriyah, Thi Qar, Iraq

Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin

Phase 1
Completed
Conditions
Nausea
Interventions
Drug: Doxylamine + Pyridoxine
Drug: Diclectin
First Posted Date
2024-04-02
Last Posted Date
2024-06-05
Lead Sponsor
Valenta Pharm JSC
Target Recruit Count
28
Registration Number
NCT06342778
Locations
🇷🇺

State budgetary health care institution Yaroslavl region "Clinical Hospital № 3", Yaroslavl, Russian Federation

Effect of Pyridoxine as Add-on Therapy in OCD Patients

Not Applicable
Recruiting
Conditions
OCD
Interventions
Drug: Pyridoxine
Drug: Placebo
First Posted Date
2024-02-06
Last Posted Date
2024-02-06
Lead Sponsor
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Target Recruit Count
76
Registration Number
NCT06244121
Locations
🇧🇩

Sumaiya Nousheen, Dhaka, Bangladesh

Clinical Analysis of Vitamin B6 in Sepsis

First Posted Date
2023-08-23
Last Posted Date
2023-08-23
Lead Sponsor
The First People's Hospital of Huzhou
Target Recruit Count
128
Registration Number
NCT06008223
Locations
🇨🇳

Wen-Ming Feng, Huzhou, Zhejiang, China

An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM

First Posted Date
2023-08-16
Last Posted Date
2024-08-14
Lead Sponsor
Queen Mary University of London
Target Recruit Count
1266
Registration Number
NCT05994742
Locations
🇿🇲

UTH - University Teaching Hospital, Lusaka, Zambia

🇿🇼

Chitungwiza Central Hospital, Harare, Zimbabwe

🇿🇼

Sally Mugabe Hospital, Harare, Zimbabwe

and more 1 locations

The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents

Phase 3
Recruiting
Conditions
Morning Sickness
Interventions
Drug: Placebo
Drug: Bonjesta
First Posted Date
2022-03-21
Last Posted Date
2023-09-13
Lead Sponsor
Duchesnay Inc.
Target Recruit Count
274
Registration Number
NCT05289557
Locations
🇺🇸

Maximos OBGYN, League City, Texas, United States

🇺🇸

Advances in Health, Pearland, Texas, United States

🇺🇸

Emerald Coast OB/GYN Clinical Research, Panama City, Florida, United States

and more 7 locations

Lactation Inhibition, the Efficiency of Vitamin B6 Versus Cabergoline

Not Applicable
Completed
Conditions
Lactation Suppressed
Interventions
Drug: Cabergoline
Drug: Pyridoxine
First Posted Date
2021-08-27
Last Posted Date
2022-11-14
Lead Sponsor
HaEmek Medical Center, Israel
Target Recruit Count
89
Registration Number
NCT05024422
Locations
🇮🇱

HaEmek Medical Center, Afula, Israel

Effect of Pyridoxine on Behavioral Adverse Events of Levetiracetam

First Posted Date
2021-08-17
Last Posted Date
2022-03-29
Lead Sponsor
Nasim Tabrizi
Target Recruit Count
30
Registration Number
NCT05008354
Locations
🇮🇷

Bu Ali Sina Hospital, Sari, Mazandaran, Iran, Islamic Republic of

Effectiveness of Acupuncture and Doxylamine/Pyridoxine for Moderate to Severe Nausea and Vomiting in Pregnancy

First Posted Date
2020-05-26
Last Posted Date
2022-04-04
Lead Sponsor
Xiaoke Wu
Target Recruit Count
352
Registration Number
NCT04401384
Locations
🇨🇳

Heilongjiang provincial hospital, Harbin, Heilongjiang, China

🇨🇳

First Affiliated Hospital of Heilongjiang Chinese Medicine University, Harbin, Heilongjiang, China

🇨🇳

Mudanjaing Maternal and Child Health Hospital, Mudanjiang, Heilongjiang, China

and more 10 locations

Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics

First Posted Date
2018-12-31
Last Posted Date
2019-12-18
Lead Sponsor
Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Target Recruit Count
45
Registration Number
NCT03790345
Locations
🇧🇷

Núcleo de Pesquisa e Desenvolvimento de Medicamentos - UFC, Fortaleza, CE, Brazil

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