Antithymocyte immunoglobulin (rabbit)
- Generic Name
- Antithymocyte immunoglobulin (rabbit)
- Brand Names
- -
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 308067-60-9
- Unique Ingredient Identifier
- D7RD81HE4W
- Background
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.
- Indication
For prevention of renal transplant rejection
- Associated Conditions
- Rejection Acute Renal
- Associated Therapies
- -
Autologous Transplant To End NMO Spectrum Disorder
- First Posted Date
- 2019-02-04
- Last Posted Date
- 2019-11-20
- Lead Sponsor
- Northwestern University
- Registration Number
- NCT03829566
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States
Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies
- Conditions
- Interventions
- First Posted Date
- 2019-01-28
- Last Posted Date
- 2019-02-01
- Lead Sponsor
- Hospital Israelita Albert Einstein
- Target Recruit Count
- 50
- Registration Number
- NCT03818334
- Locations
- 🇧🇷
Hospita Israelita Albert Eintein, São Paulo, SP, Brazil
Antithymocyte Globulin and Azathioprine Versus Basiliximab and Mycophenolate Mofetil in Living Donor Kidney Transplantation
- Conditions
- Interventions
- First Posted Date
- 2018-12-28
- Last Posted Date
- 2019-01-03
- Lead Sponsor
- University of Khartoum
- Target Recruit Count
- 300
- Registration Number
- NCT03789006
- Locations
- 🇸🇩
Doctor Salma Center for Kidney Diseases, Khartoum, Sudan
PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis
- First Posted Date
- 2018-09-28
- Last Posted Date
- 2019-10-28
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Target Recruit Count
- 260
- Registration Number
- NCT03689465
- Locations
- 🇨🇳
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
🇨🇳Xiangya Hospital, Central South University, Changsha, Hunan, China
🇨🇳Department of Hematology,Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia
- First Posted Date
- 2018-07-26
- Last Posted Date
- 2022-04-12
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 3
- Registration Number
- NCT03600909
- Locations
- 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
🇺🇸Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
🇺🇸Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)
- Conditions
- Interventions
- First Posted Date
- 2018-07-24
- Last Posted Date
- 2024-06-12
- Lead Sponsor
- St. Jude Children's Research Hospital
- Target Recruit Count
- 4
- Registration Number
- NCT03597594
- Locations
- 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
Cardiac Safe Transplants for Systemic Sclerosis
- First Posted Date
- 2018-07-20
- Last Posted Date
- 2020-08-12
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 9
- Registration Number
- NCT03593902
- Locations
- 🇺🇸
Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States
🇺🇸Northwestern University, Chicago, Illinois, United States
Low Dose ATG Plus Low Dose PTCy as GVHD Prophylaxis in Haplo-HSCT
- First Posted Date
- 2018-01-10
- Last Posted Date
- 2019-04-16
- Target Recruit Count
- 100
- Registration Number
- NCT03395860
- Locations
- 🇨🇳
Shanghai First People's HOSPITAL, Shanghai, Shanghai, China
Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation
- First Posted Date
- 2018-01-02
- Last Posted Date
- 2022-11-25
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 27
- Registration Number
- NCT03388008
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
🇺🇸Houston Methodist Hospital, Houston, Texas, United States
Maximizing Outcome of Multiple Sclerosis Transplantation
- First Posted Date
- 2017-11-17
- Last Posted Date
- 2021-01-11
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 66
- Registration Number
- NCT03342638
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
Drug Development Updates
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