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AZD-1981

Generic Name
AZD-1981
Drug Type
Small Molecule
Chemical Formula
C19H17ClN2O3S
CAS Number
802904-66-1
Unique Ingredient Identifier
2AD53WQ2CX
Background

AZD1981 has been used in trials studying the treatment and basic science of Asthma, Postmenopausal, Pharmakokinetic, Asthma Patients, and Drug Interaction, among others.

Efficacy and Safety of Chemoattractant Receptor-homologous Molecule Expressed on T Helper Type 2 (CRTh2) Antagonist AZD1981 in Chronic Idiopathic Urticaria (CIU) Antihistamines

Phase 2
Completed
Conditions
Chronic Idiopathic Urticaria
Interventions
Drug: Placebo
First Posted Date
2014-01-09
Last Posted Date
2017-07-12
Lead Sponsor
Johns Hopkins University
Target Recruit Count
38
Registration Number
NCT02031679
Locations
πŸ‡ΊπŸ‡Έ

Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland, United States

A Drug-Drug Interaction Study Between AZD1981 and Pravastatin to Study the Effect of AZD1981 on the Kinetics of Pravastatin

Phase 1
Completed
Conditions
Drug Interaction
Interventions
First Posted Date
2010-12-06
Last Posted Date
2011-04-29
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT01254461
Locations
πŸ‡ΈπŸ‡ͺ

Research Site, Uppsala, Sweden

A Drug-Drug Interaction Study to Study the Effect of AZD1981 on Warfarin

Phase 1
Completed
Conditions
Pharmakokinetic
Interventions
First Posted Date
2010-09-10
Last Posted Date
2011-02-09
Lead Sponsor
AstraZeneca
Target Recruit Count
28
Registration Number
NCT01199341
Locations
πŸ‡ΈπŸ‡ͺ

Research Site, Uppsala, Sweden

Investigation of Efficacy, Safety and Tolerability of Once and Twice Daily Doses of AZD1981 in Asthmatic Patients

Phase 2
Completed
Conditions
Asthma Patients
Interventions
Drug: Placebo
First Posted Date
2010-09-09
Last Posted Date
2013-11-06
Lead Sponsor
AstraZeneca
Target Recruit Count
1144
Registration Number
NCT01197794
Locations
πŸ‡ΊπŸ‡¦

Research Site, Zaporozhye, Ukraine

A Drug-drug Interaction Study to Investigate the Effects of AZD1981 on the Metabolism and Pharmacodynamics of Oral Contraceptives

Phase 1
Completed
Conditions
Oral Contraceptives
Interventions
Drug: Neovletta 21/28
Drug: Placebo AZD1981
First Posted Date
2010-04-26
Last Posted Date
2010-11-18
Lead Sponsor
AstraZeneca
Target Recruit Count
28
Registration Number
NCT01110525
Locations
πŸ‡ΈπŸ‡ͺ

Research Site, Uppsala, Sweden

Study to Assess the Metabolism, Excretion and Pharmacokinetics of [14C]AZD1981 in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2010-01-28
Last Posted Date
2010-11-18
Lead Sponsor
AstraZeneca
Target Recruit Count
4
Registration Number
NCT01058447

AZD1981 Bioavailability Study of Intravenous (IV) and Oral Formulations

Phase 1
Completed
Conditions
Healthy
Postmenopausal
Surgically Sterile Women
Interventions
First Posted Date
2009-06-11
Last Posted Date
2009-07-30
Lead Sponsor
AstraZeneca
Target Recruit Count
14
Registration Number
NCT00918398
Locations
πŸ‡ΈπŸ‡ͺ

Research Site, Uppsala, Sweden

AZD1981 Midazolam CYP4503A Induction Study

Phase 1
Completed
Conditions
Healthy Male Volunteer
Interventions
First Posted Date
2009-03-11
Last Posted Date
2009-04-10
Lead Sponsor
AstraZeneca
Target Recruit Count
28
Registration Number
NCT00859352
Locations
πŸ‡ΈπŸ‡ͺ

Research Site, Uppsala, Sweden

14729-D9831C00002- 1 Month Biopsy Study

Phase 2
Completed
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Drug: Placebo
First Posted Date
2008-10-06
Last Posted Date
2014-02-28
Lead Sponsor
AstraZeneca
Target Recruit Count
52
Registration Number
NCT00766415
Locations
πŸ‡¬πŸ‡§

Research Site, Newcastle upon Tyne, United Kingdom

One Month Dose Response Study of AZD1981 in Asthma Patients Uncontrolled on Inhaled Steroids

Phase 2
Completed
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2008-09-25
Last Posted Date
2014-02-26
Lead Sponsor
AstraZeneca
Target Recruit Count
368
Registration Number
NCT00758589
Locations
πŸ‡΅πŸ‡±

Research Site, Wroclaw, Poland

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