Pamidronic acid

Generic Name
Pamidronic acid
Brand Names
Pamisol
Drug Type
Small Molecule
Chemical Formula
C3H11NO7P2
CAS Number
40391-99-9
Unique Ingredient Identifier
OYY3447OMC
Background

Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are ...

Indication

Pamidronate is indicated to treat moderate to severe hypercalcemia of malignancy, moderate to severe Paget's disease of bone, osteolytic bone metastases of breast cancer, and osteolytic lesions of multiple myeloma.

Associated Conditions
Hypercalcemia of Malignancy, Osteolytic lesion, Paget’s Disease, Osteolytic Bone metastases
Associated Therapies
-

Combination Bisphosphonate and Anti-Angiogenesis Therapy With Pamidronate and Thalidomide

Phase 2
Completed
Conditions
First Posted Date
2004-05-25
Last Posted Date
2010-07-05
Lead Sponsor
University of Arkansas
Target Recruit Count
20
Registration Number
NCT00083408
Locations
🇺🇸

University of Arkansas for Medical Sciences/MIRT, Little Rock, Arkansas, United States

Combination Bisphosphonate and Anti-Angiogenesis Therapy With Pamidronate and Thalidomide

First Posted Date
2004-05-24
Last Posted Date
2015-06-24
Lead Sponsor
University of Arkansas
Target Recruit Count
83
Registration Number
NCT00083382
Locations
🇺🇸

University of Arkansas for Medical Sciences/MIRT, Little Rock, Arkansas, United States

Prevention of Steroid-Induced Osteoporosis in Children

Phase 1
Terminated
Conditions
First Posted Date
2001-08-16
Last Posted Date
2007-12-19
Lead Sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Target Recruit Count
40
Registration Number
NCT00022841
Locations
🇺🇸

Washington University Medical School-St. Louis Children's Hospital, St. Louis, Missouri, United States

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