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Triazavirin

Generic Name
Triazavirin
Drug Type
Small Molecule
Chemical Formula
C5H4N6O3S
CAS Number
123606-06-4
Unique Ingredient Identifier
F2HTG1MH2D
Background

Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain. It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.

Indication

Triazavirin was developed in Russia as a potential treatment of Influenza A and B infections.

Evaluation of The Efficacy of Triazavirin Versus Oseltamivir in Egyptian Patients Infected With COVID-19

Phase 4
Conditions
Covid19
Interventions
First Posted Date
2021-07-22
Last Posted Date
2021-07-22
Lead Sponsor
Ain Shams University
Target Recruit Count
80
Registration Number
NCT04973462
Locations
🇪🇬

Fever Hospital of the Egyptian Armed Forces, Cairo, Egypt

PHRU CoV01 A Trial of Triazavirin (TZV) for the Treatment of Mild-moderate COVID-19

Phase 2
Terminated
Conditions
Covid19
Interventions
First Posted Date
2020-10-09
Last Posted Date
2022-08-02
Lead Sponsor
Wits Health Consortium (Pty) Ltd
Target Recruit Count
74
Registration Number
NCT04581915
Locations
🇿🇦

The Perinatal HIV Research Unit - Matlosana, Klerksdorp, North West Province, South Africa

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