MedPath

Chlorotoxin

Generic Name
Chlorotoxin
Drug Type
Biotech
CAS Number
163515-35-3
Unique Ingredient Identifier
06UV5RFW57
Background

Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

Phase 1
Recruiting
Conditions
Recurrent Glioblastoma
Recurrent WHO Grade III Glioma
Recurrent Malignant Glioma
Recurrent WHO Grade II Glioma
Interventions
First Posted Date
2020-01-02
Last Posted Date
2024-11-29
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
36
Registration Number
NCT04214392
Locations
🇺🇸

City of Hope Medical Center, Duarte, California, United States

Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma

Phase 1
Conditions
Malignant Glioma
Glioblastoma Multiforme
GBM
Astrocytoma
Oligodendroglioma
Interventions
First Posted Date
2008-01-11
Last Posted Date
2009-07-17
Lead Sponsor
TransMolecular
Target Recruit Count
36
Registration Number
NCT00591058
Locations
🇺🇸

Washington University, St. Louis, Missouri, United States

🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

University of Alabama, Birmingham, Alabama, United States

and more 4 locations
© Copyright 2025. All Rights Reserved by MedPath