Prednisolone
- Generic Name
- Prednisolone
- Brand Names
- Millipred Dp 6 Day
- Drug Type
- Small Molecule
- Chemical Formula
- C21H28O5
- CAS Number
- 50-24-8
- Unique Ingredient Identifier
- 9PHQ9Y1OLM
- Background
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Prednisolone was granted FDA approval on 21 June 1955.
- Indication
Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.
- Associated Conditions
- Acute Gouty Arthritis, Acute Leukemia, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Contact Dermatitis, Allergic Skin Reaction, Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonia, Aspiration Pneumonitis, Atopic Dermatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Burns, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Conjunctivitis, Contact Dermatitis, Corneal injuries, Corneal ulceration, Crohn's Disease (CD), Cyclitis, Dermatomyositis (DM), Dermatosis of the Ear Canal, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Exacerbation of COPD, Exacerbation of asthma, Eye inflammation caused by Cataract Surgery, Eye inflammation caused by Infection, Fissure;Anal, Herpes Zoster Keratitis, Hot Water Burns (Scalds), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Inflamed External Hemorrhoid, Inflamed Hemorrhoids, Internal, Inflammatory Reaction caused by susceptible Bacterial Infections, Iridocyclitis, Iritis, Itching caused by susceptible Bacterial Infections, Keratitis, Loeffler's syndrome, Lymphoma, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Otic Eczema, Pemphigus, Perennial Allergic Rhinitis (PAR), Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Posterior Uveitis, Posttraumatic Osteoarthritis, Proctitis, Proteinuria, Pruritus, Pruritus Ani, Psoriatic Arthritis, Pulmonary Tuberculosis (TB), Pure Red Cell Aplasia, Rash, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Rosacea, Seasonal Allergic Rhinitis, Secondary Adrenal Insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Asthma, Sjogren's Syndrome (SS), Stevens-Johnson Syndrome, Superficial punctate keratitis, Synovitis, Systemic Lupus Erythematosus, Transplanted Organ Rejection, Trichinosis, Tuberculosis (TB), Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Rheumatic heart disease, unspecified, Acute Tenosynovitis, Anal eczema, Bacterial skin infections, Exfoliative erythroderma, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Primary adrenocoritical insufficiency, Severe Psoriasis, Severe Seborrhoeic dermatitis, Severe alcoholic liver disease, Steroid-responsive inflammation of the eye, Subacute Bursitis, Susceptible Bacterial Infections, Symptomatic Sarcoidosis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- -
PREDnisolone-induced Beta-cell Dysfunction Prevented by EXenatide
- Conditions
- Interventions
- First Posted Date
- 2008-08-29
- Last Posted Date
- 2010-01-13
- Lead Sponsor
- Amsterdam UMC, location VUmc
- Target Recruit Count
- 8
- Registration Number
- NCT00744224
- Locations
- 🇳🇱
VU University Medical Center, Amsterdam, Noord-Holland, Netherlands
Viral Inception of Asthma: Prospective Study From Infancy to School-age
- Conditions
- First Posted Date
- 2008-08-11
- Last Posted Date
- 2011-08-12
- Lead Sponsor
- University of Turku
- Target Recruit Count
- 200
- Registration Number
- NCT00731575
- Locations
- 🇫🇮
Dept of Pediatrics, Turku University Hospital, Turku, Finland
Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae
- First Posted Date
- 2008-07-28
- Last Posted Date
- 2008-07-29
- Lead Sponsor
- Mashhad University of Medical Sciences
- Target Recruit Count
- 30
- Registration Number
- NCT00723268
- Locations
- 🇮🇷
Mashhad Dental school, Mashhad, Khorasan Razavi, Iran, Islamic Republic of
Combination Chemotherapy and Rituximab in Treating Patients With Primary Mediastinal Diffuse Large B-Cell Lymphoma
- Conditions
- Interventions
- First Posted Date
- 2008-06-04
- Last Posted Date
- 2009-07-08
- Target Recruit Count
- 120
- Registration Number
- NCT00689845
- Locations
- 🇬🇧
Leeds Cancer Centre at St. James's University Hospital, Leeds, England, United Kingdom
🇬🇧Christie Hospital, Manchester, England, United Kingdom
🇬🇧Southampton General Hospital, Southampton, England, United Kingdom
Cyclophosphamide, Methotrexate, and Prednisolone With or Without Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2008-06-02
- Last Posted Date
- 2009-06-17
- Lead Sponsor
- National Cancer Centre, Singapore
- Target Recruit Count
- 70
- Registration Number
- NCT00687648
- Locations
- 🇸🇬
National Cancer Centre - Singapore, Singapore, Singapore
Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma
- Conditions
- Interventions
- First Posted Date
- 2008-05-15
- Last Posted Date
- 2024-05-08
- Lead Sponsor
- University College, London
- Target Recruit Count
- 1202
- Registration Number
- NCT00678327
- Locations
- 🇬🇧
Southampton General Hospital, Southampton, England, United Kingdom
High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma
- Conditions
- First Posted Date
- 2008-05-01
- Last Posted Date
- 2013-08-26
- Lead Sponsor
- Cancer Research UK
- Target Recruit Count
- 60
- Registration Number
- NCT00669812
- Locations
- 🇬🇧
Sir James Spence Institute of Child Health at Royal Victoria Infirmary, Newcastle-Upon-Tyne, England, United Kingdom
Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma
- First Posted Date
- 2008-04-25
- Last Posted Date
- 2014-12-04
- Lead Sponsor
- University College, London
- Target Recruit Count
- 47
- Registration Number
- NCT00666484
- Locations
- 🇬🇧
University College Hospital - London, London, England, United Kingdom
🇬🇧Leeds Cancer Centre at St. James's University Hospital, Leeds, England, United Kingdom
🇬🇧King's College Hospital, London, England, United Kingdom
Prednisolone Pharmacokinetics in Severe Asthma
- First Posted Date
- 2008-04-21
- Last Posted Date
- 2019-11-20
- Lead Sponsor
- Imperial College London
- Target Recruit Count
- 5
- Registration Number
- NCT00662298
- Locations
- 🇬🇧
Asthma Laboratory, Royal Brompton Hospital, London, United Kingdom
Rituximab, Combination Chemotherapy, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed Follicular Non-Hodgkin Lymphoma
- First Posted Date
- 2008-03-18
- Last Posted Date
- 2022-01-06
- Lead Sponsor
- University of Southampton
- Target Recruit Count
- 1
- Registration Number
- NCT00637832
- Locations
- 🇬🇧
Mount Vernon Cancer Centre at Mount Vernon Hospital, Northwood, England, United Kingdom
🇬🇧Dorset Cancer Centre, Poole Dorset, England, United Kingdom
🇬🇧Southampton General Hospital, Southampton, England, United Kingdom
Drug Development Updates
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