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TETRACYCLINE HYDROCHLORIDE

TETRACYCLINE HYDROCHLORIDE CAPSULES, USP For Oral Use Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of tetracycline hydrochloride and other antibacterial drugs, tetracycline hydrochloride should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Approved
Approval ID

fb338af1-2b1b-413f-9653-10f318dbc4b3

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Oct 21, 2022

Manufacturers
FDA

Strides Pharma Science Limited

DUNS: 650738743

Products 2

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

TETRACYCLINE HYDROCHLORIDE

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code64380-890
Application NumberANDA212635
Product Classification
M
Marketing Category
C73584
G
Generic Name
TETRACYCLINE HYDROCHLORIDE
Product Specifications
Route of AdministrationORAL
Effective DateOctober 21, 2022
FDA Product Classification

INGREDIENTS (14)

LACTOSE MONOHYDRATEInactive
Code: EWQ57Q8I5X
Classification: IACT
TETRACYCLINE HYDROCHLORIDEActive
Quantity: 250 mg in 1 1
Code: P6R62377KV
Classification: ACTIB
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
SODIUM STARCH GLYCOLATE TYPE A POTATOInactive
Code: 5856J3G2A2
Classification: IACT
STARCH, PREGELATINIZED CORNInactive
Code: O8232NY3SJ
Classification: IACT
TITANIUM DIOXIDEInactive
Code: 15FIX9V2JP
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
D&C YELLOW NO. 10Inactive
Code: 35SW5USQ3G
Classification: IACT
GELATINInactive
Code: 2G86QN327L
Classification: IACT
FD&C YELLOW NO. 6Inactive
Code: H77VEI93A8
Classification: IACT
FERROSOFERRIC OXIDEInactive
Code: XM0M87F357
Classification: IACT
SHELLACInactive
Code: 46N107B71O
Classification: IACT
POTASSIUM HYDROXIDEInactive
Code: WZH3C48M4T
Classification: IACT

TETRACYCLINE HYDROCHLORIDE

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code64380-891
Application NumberANDA212635
Product Classification
M
Marketing Category
C73584
G
Generic Name
TETRACYCLINE HYDROCHLORIDE
Product Specifications
Route of AdministrationORAL
Effective DateOctober 21, 2022
FDA Product Classification

INGREDIENTS (14)

TETRACYCLINE HYDROCHLORIDEActive
Quantity: 500 mg in 1 1
Code: P6R62377KV
Classification: ACTIB
LACTOSE MONOHYDRATEInactive
Code: EWQ57Q8I5X
Classification: IACT
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
SODIUM STARCH GLYCOLATE TYPE A POTATOInactive
Code: 5856J3G2A2
Classification: IACT
STARCH, PREGELATINIZED CORNInactive
Code: O8232NY3SJ
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
TITANIUM DIOXIDEInactive
Code: 15FIX9V2JP
Classification: IACT
D&C YELLOW NO. 10Inactive
Code: 35SW5USQ3G
Classification: IACT
FD&C YELLOW NO. 6Inactive
Code: H77VEI93A8
Classification: IACT
FERROSOFERRIC OXIDEInactive
Code: XM0M87F357
Classification: IACT
GELATINInactive
Code: 2G86QN327L
Classification: IACT
SHELLACInactive
Code: 46N107B71O
Classification: IACT
POTASSIUM HYDROXIDEInactive
Code: WZH3C48M4T
Classification: IACT

Drug Labeling Information

DESCRIPTION SECTION

LOINC: 34089-3Updated: 3/9/2020

DESCRIPTION

Tetracycline is a yellow, odorless, crystalline powder. Tetracycline is stable in air but exposure to strong sunlight causes it to darken. Its potency is affected in solutions of pH below 2 and is rapidly destroyed by alkali hydroxide solutions. Tetracycline is very slightly soluble in water, freely soluble in dilute acid and in alkali hydroxide solutions, sparingly soluble in alcohol, and practically insoluble in chloroform and in ether. The chemical name for tetracycline hydrochloride is 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,-12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecar- boxamide monohydrochloride. Its structural formula is as follows:

structural formula

structural formula

Each capsule, for oral administration, contains 250 mg or 500 mg tetracycline hydrochloride.

**Inactive Ingredients:**Lactose Monohydrate, Colloidal Silicon Dioxide, Sodium Starch Glycolate, Pregelatinised Starch and Magnesium Stearate.

The 250 mg and 500 mg capsule shells contain D&C yellow no. 10, FD&C blue no. 1, FD&C yellow no. 6, gelatin, and titanium dioxide.

The imprinting ink for the 250 mg and 500 mg capsules contains Shellac, Black Iron Oxide and Potassium Hydroxide.

USP Dissolution Test 2.

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TETRACYCLINE HYDROCHLORIDE - FDA Drug Approval Details