四环素 (Pylera, Sumycin)

概览

Tetracycline is an antibiotic used to treat a wide variety of susceptible infections.

作用机制

Tetracycline passively diffuses through porin channels in the bacterial membrane and reversibly binds to the 30S ribosomal subunit, preventing binding of tRNA to the mRNA-ribosome complex, and thus interfering with protein synthesis.

适应症

Used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, rickettsialpox and Brill-Zinsser disease. May be used to treat infections caused by Chlamydiae spp., B. burgdorferi (Lyme disease), and upper respiratory infections caused by typical (S. pneumoniae, H. influenzae, and M. catarrhalis) and atypical organisms (C. pneumoniae, M. pneumoniae, L. pneumophila). May also be used to treat acne. Tetracycline may be an alternative drug for people who are allergic to penicillin.

• Acinetobacter Infections
• Actinomycosis
• Anthrax
• Bacterial Infections
• Bartonellosis
• Brucellosis
• Campylobacter Infection
• Chancroid
• Chlamydial Infections
• Cholera (Disorder)
• Clostridium Infections
• Conjunctivitis, Inclusion