MedPath

I-Sleep

I-Sleep 4844L

Approved
Approval ID

c6f053fe-8b59-7226-e053-2995a90a8093

Product Type

HUMAN OTC DRUG LABEL

Effective Date

Sep 18, 2025

Manufacturers
FDA

Newton Laboratories, Inc.

DUNS: 788793610

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Absinthium, Anacardium orientale, Arg. nit., Arsenicum alb., Belladonna, Bryonia, Calc. carb., Camphora, Chamomilla, Cimicifuga, Cinchona, Coffea cruda, Cypripedium, Gelsemium, Humulus, Hyoscyamus, Ignatia, Kali brom., Nux vom., Passiflora, Pulsatilla, Scutellaria lateriflora, Sepia, Thuja occ., Valeriana

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code55714-4844
Product Classification
G
Generic Name
Absinthium, Anacardium orientale, Arg. nit., Arsenicum alb., Belladonna, Bryonia, Calc. carb., Camphora, Chamomilla, Cimicifuga, Cinchona, Coffea cruda, Cypripedium, Gelsemium, Humulus, Hyoscyamus, Ignatia, Kali brom., Nux vom., Passiflora, Pulsatilla, Scutellaria lateriflora, Sepia, Thuja occ., Valeriana
Product Specifications
Route of AdministrationORAL
Effective DateSeptember 18, 2025
FDA Product Classification

INGREDIENTS (27)

ALCOHOLInactive
Code: 3K9958V90M
Classification: IACT
WORMWOODActive
Quantity: 20 [hp_X] in 1 mL
Code: F84709P2XV
Classification: ACTIB
SEMECARPUS ANACARDIUM JUICEActive
Quantity: 20 [hp_X] in 1 mL
Code: Y0F0BU8RDU
Classification: ACTIB
SILVER NITRATEActive
Quantity: 20 [hp_X] in 1 mL
Code: 95IT3W8JZE
Classification: ACTIB
ARSENIC TRIOXIDEActive
Quantity: 20 [hp_X] in 1 mL
Code: S7V92P67HO
Classification: ACTIB
ATROPA BELLADONNAActive
Quantity: 20 [hp_X] in 1 mL
Code: WQZ3G9PF0H
Classification: ACTIB
BRYONIA ALBA ROOTActive
Quantity: 20 [hp_X] in 1 mL
Code: T7J046YI2B
Classification: ACTIB
OYSTER SHELL CALCIUM CARBONATE, CRUDEActive
Quantity: 20 [hp_X] in 1 mL
Code: 2E32821G6I
Classification: ACTIB
CAMPHOR (NATURAL)Active
Quantity: 20 [hp_X] in 1 mL
Code: N20HL7Q941
Classification: ACTIB
MATRICARIA CHAMOMILLAActive
Quantity: 20 [hp_X] in 1 mL
Code: G0R4UBI2ZZ
Classification: ACTIB
BLACK COHOSHActive
Quantity: 20 [hp_X] in 1 mL
Code: K73E24S6X9
Classification: ACTIB
CINCHONA OFFICINALIS BARKActive
Quantity: 20 [hp_X] in 1 mL
Code: S003A158SB
Classification: ACTIB
ARABICA COFFEE BEANActive
Quantity: 20 [hp_X] in 1 mL
Code: 3SW678MX72
Classification: ACTIB
CYPRIPEDIUM PARVIFLORUM VAR. PUBESCENS ROOTActive
Quantity: 20 [hp_X] in 1 mL
Code: 21Y9GZ1LZA
Classification: ACTIB
GELSEMIUM SEMPERVIRENS ROOTActive
Quantity: 20 [hp_X] in 1 mL
Code: 639KR60Q1Q
Classification: ACTIB
HOPSActive
Quantity: 20 [hp_X] in 1 mL
Code: 01G73H6H83
Classification: ACTIB
HYOSCYAMUS NIGERActive
Quantity: 20 [hp_X] in 1 mL
Code: 4WRK2153H3
Classification: ACTIB
STRYCHNOS IGNATII SEEDActive
Quantity: 20 [hp_X] in 1 mL
Code: 1NM3M2487K
Classification: ACTIB
POTASSIUM BROMIDEActive
Quantity: 20 [hp_X] in 1 mL
Code: OSD78555ZM
Classification: ACTIB
STRYCHNOS NUX-VOMICA SEEDActive
Quantity: 20 [hp_X] in 1 mL
Code: 269XH13919
Classification: ACTIB
PASSIFLORA INCARNATA FLOWERING TOPActive
Quantity: 20 [hp_X] in 1 mL
Code: CLF5YFS11O
Classification: ACTIB
ANEMONE PULSATILLAActive
Quantity: 20 [hp_X] in 1 mL
Code: I76KB35JEV
Classification: ACTIB
SCUTELLARIA LATERIFLORA WHOLEActive
Quantity: 20 [hp_X] in 1 mL
Code: 7BP4DH5PDC
Classification: ACTIB
SEPIA OFFICINALIS JUICEActive
Quantity: 20 [hp_X] in 1 mL
Code: QDL83WN8C2
Classification: ACTIB
THUJA OCCIDENTALIS LEAFY TWIGActive
Quantity: 20 [hp_X] in 1 mL
Code: 1NT28V9397
Classification: ACTIB
VALERIANActive
Quantity: 11 [hp_X] in 1 mL
Code: JWF5YAW3QW
Classification: ACTIB
WATERInactive
Code: 059QF0KO0R
Classification: IACT

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 9/18/2025

PACKAGE LABEL

Package label

INDICATIONS & USAGE SECTION

LOINC: 34067-9Updated: 9/18/2025

INDICATIONS & USAGE SECTION

Formulated for symptoms associated with sleeplessness such as frequent waking, restlessness and the inability to fall asleep or return to sleep after waking.

DOSAGE & ADMINISTRATION SECTION

LOINC: 34068-7Updated: 2/1/2021

DOSAGE & ADMINISTRATION SECTION

**Directions:**Ages 12 and up, take 6 drops by mouth (ages 0 to 11, give 3 drops) one hour before bedtime, and then again at bedtime. Repeat as needed or as directed by a health professional.

OTC - ACTIVE INGREDIENT SECTION

LOINC: 55106-9Updated: 2/1/2021

OTC - ACTIVE INGREDIENT SECTION

Equal parts of Passiflora incarnata 11x, Valeriana officinalis 11x, Absinthium 20x, Anacardium orientale 20x, Argentum nitricum 20x, Bryonia 20x, Calcarea carbonica 20x, Camphora 20x, Chamomilla 20x, Cimicifuga racemosa 20x, Cinchona officinalis 20x, Coffea cruda 20x, Cypripedium pubescen 20x, Gelsemium sempervirens 20x, Humulus lupulus 20x, Hyoscyamus niger 20x, Ignatia amara 20x, Kali bromatum 20x, Passiflora incarnata 20x, Pulsatilla 20x, Scutellaria lateriflora 20x, Sepia 20x, Thuja occidentalis 20x, Arsenicum album 20x, Belladonna 20x, Nux vomica 20x

OTC - PURPOSE SECTION

LOINC: 55105-1Updated: 9/18/2025

OTC - PURPOSE SECTION

Formulated for symptoms associated with sleeplessness such as frequent waking, restlessness and the inability to fall asleep or return to sleep after waking.

INACTIVE INGREDIENT SECTION

LOINC: 51727-6Updated: 2/1/2021

INACTIVE INGREDIENT SECTION

Inactive Ingredients: USP Purified Water; USP Gluten-free, non-GMO, organic cane alcohol 20%.

OTC - QUESTIONS SECTION

LOINC: 53413-1Updated: 2/1/2021

QUESTIONS SECTION

newtonlabs.net – Questions? 800.448.7256

Newton Laboratories, Inc. FDA Est # 1051203 - Conyers, GA 30013

WARNINGS SECTION

LOINC: 34071-1Updated: 2/1/2021

WARNINGS SECTION

WARNINGS: Keep out of reach of children.** Do not useif tamper-evident seal is broken or missing. If symptoms worsen or persist for more than a few days, consult a doctor. Ifpregnant or breast-feeding**, ask a doctor before use.

OTC - PREGNANCY OR BREAST FEEDING SECTION

LOINC: 53414-9Updated: 2/1/2021

OTC - PREGNANCY OR BREAST FEEDING SECTION

Ifpregnant or breast-feeding, ask a doctor before use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

LOINC: 50565-1Updated: 2/1/2021

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children.

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I-Sleep - FDA Drug Approval Details