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HSA Approval

FORTACIN CUTANEOUS SPRAY SOLUTION 7.5MG/dose + 2.5MG/dose

SIN16538P

FORTACIN CUTANEOUS SPRAY SOLUTION 7.5MG/dose + 2.5MG/dose

FORTACIN CUTANEOUS SPRAY SOLUTION 7.5MG/dose + 2.5MG/dose

July 5, 2022

ORIENT EUROPHARMA PTE LTD

ORIENT EUROPHARMA PTE LTD

Regulatory Information

HSA regulatory responsibility and product classification details

Regulatory Responsibility

RegistrantORIENT EUROPHARMA PTE LTD
Licence HolderORIENT EUROPHARMA PTE LTD

Product Classification

D
Drug Type
Therapeutic
F
Forensic Class
Prescription Only
HSA Singapore Classification

Formulation Information

SPRAY, METERED

**4.2 Posology and method of administration** Posology The recommended dose is 3 actuations applied to cover the glans penis. Each dose consists of a total of 22.5 mg lidocaine and 7.5 mg prilocaine per application (1 dose is equal to 3 actuations). A maximum of 3 doses can be used within 24 hours with at least 4 hours between doses. Special populations _Elderly_ Dosage adjustments are not required in the elderly. There is limited data on the efficacy and safety of Fortacin in patients 65 years and over. _Renal impairment_ Clinical studies have not been performed in patients with impaired renal function, however due to its method of administration and very low systemic absorption, no dosage adjustment is required. _Hepatic impairment_ Clinical studies have not been performed in patients with impaired hepatic function, however due to its method of administration and very low systemic absorption, no dosage adjustment is required. Caution is advised in case of severe hepatic impairment (see section 4.4 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_). _Paediatric population_ There is no relevant use of Fortacin in the paediatric population for the indication of treatment of primary premature ejaculation in adult men. Method of administration Cutaneous use. Fortacin is only indicated for application to the glans penis. Before initial use, the spray container should be briefly shaken and then primed by spraying it into the air three times. Before each subsequent use, it should be briefly shaken and then the spray container should be re-primed by spraying it once. Any foreskin should be retracted from the glans penis. Once the can is held upright (valve up), 1 dose of Fortacin should be applied to the entire glans penis, by actuating the valve 3 times. One third of the glans penis should be covered with each actuation. After 5 minutes any excess spray should be wiped off prior to intercourse.

CUTANEOUS

Medical Information

**4.1 Therapeutic indications** Fortacin is indicated for the treatment of primary premature ejaculation in adult men.

**4.3 Contraindications** Hypersensitivity of the patient or their partner to the active substances or to any of the excipients listed in section 6.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_. Patients or their partner with a known history of sensitivity to local anaesthetics of the amide type.

N01BB20

combinations

Manufacturer Information

ORIENT EUROPHARMA PTE LTD

Pharmaserve (North West) Ltd

Active Ingredients

Prilocaine

2.5mg/dose

Prilocaine

Lidocaine

7.5 mg/dose

Lidocaine

Documents

Package Inserts

Fortacin Cutaneous Spray Solution PI.pdf

Approved: July 5, 2022

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FORTACIN CUTANEOUS SPRAY SOLUTION 7.5MG/dose + 2.5MG/dose - HSA Approval | MedPath