NATRILIX SR TABLET 1.5 mg

SERVIER (S) PTE LTD

SERVIER (S) PTE LTD

Therapeutic

Prescription Only

TABLET, FILM COATED

**4.2 Posology and method of administration** Posology One tablet per 24 hours, preferably in the morning, to be swallowed whole with water and not chewed. At higher doses the antihypertensive action of indapamide is not enhanced but the saluretic effect is increased. Special populations _Renal impairment (see sections 4.3 and 4.4_ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_): In severe renal failure (creatinine clearance below 30 ml/min), treatment is contraindicated. Thiazide and related diuretics are fully effective only when renal function is normal or only minimally impaired. _Hepatic impairment (see sections 4.3 and 4.4_ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_): In severe hepatic impairment, treatment is contraindicated. _Elderly (see section 4.4_ – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_): In the elderly, the plasma creatinine must be adjusted in relation to age, weight and gender. Elderly patients can be treated with Natrilix SR 1.5 mg when renal function is normal or only minimally impaired. _Paediatric population:_ The safety and efficacy of Natrilix SR 1.5 mg in children and adolescents have not been established. No data are available. Method of administration Oral use