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HSA Approval

PERTAGEN® SUSPENSION FOR INJECTION 0.5 ML/DOSE

SIN16283P

PERTAGEN® SUSPENSION FOR INJECTION 0.5 ML/DOSE

PERTAGEN® SUSPENSION FOR INJECTION 0.5 ML/DOSE

July 23, 2021

NOVEM HEALTHCARE PTE LTD

NOVEM HEALTHCARE PTE LTD

Regulatory Information

HSA regulatory responsibility and product classification details

Regulatory Responsibility

RegistrantNOVEM HEALTHCARE PTE LTD
Licence HolderNOVEM HEALTHCARE PTE LTD

Product Classification

D
Drug Type
Therapeutic
F
Forensic Class
Prescription Only
HSA Singapore Classification

Formulation Information

INJECTION, SUSPENSION

**POSOLOGY** A single 0.5 mL dose of **Pertagen®** is recommended. **Pertagen®** should be given following the current local recommendation for booster vaccination against pertussis. In accordance with 2019 WHO recommendations for routine immunization of pertussis-containing vaccine, the use of **Pertagen®** may be considered in the second or third trimester and preferably at least 15 days before the end of pregnancy. See **PREGNANCY AND LACTATION** section – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_.

INTRAMUSCULAR

Medical Information

**INDICATION** **Pertagen®** is indicated for active booster immunization against pertussis in individuals from the age of 11 years onwards. **Pertagen®** may be considered as an alternative to combined tetanus, diphtheria and acellular pertussis vaccines in persons having received multiple and frequent tetanus and diphtheria vaccine doses including persons with known hypersensitivity to tetanus (Arthus-type hypersensitivity reaction) or diphtheria vaccines.

**CONTRAINDICATION** **Pertagen®** should not be administered to individuals having shown signs of hypersensitivity or life-threatening reaction following administration of pertussis vaccines or to any components of the vaccine. Hypersensitivity to diphtheria and tetanus vaccines are not contraindication to the use of **Pertagen®**. **Pertagen®** should not be administered to individuals having experienced any encephalopathy with unknown aetiology such as coma, prolonged seizures, or decreased level of consciousness within 7 days following previous vaccination with any whooping cough vaccine. **Pertagen®** should not be administered to individuals with progressive or unstable neurological disorders, uncontrolled epilepsy or progressive encephalopathy.

J07AJ02

pertussis, purified antigen

Manufacturer Information

NOVEM HEALTHCARE PTE LTD

Bionet-Asia Co., Ltd.

Active Ingredients

Recombinant Pertussis Toxin (rPT)

5 ug/0.5 ml

Filamentous Haemagglutinin (FHA)

5 ug/0.5 ml

Documents

Package Inserts

Pertagen Suspension for Injection PI.pdf

Approved: June 28, 2022

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