Ibandronate

Generic Name
Ibandronate
Brand Names
Bondronat, Boniva, Bonviva, Iasibon, Ibandronic acid Accord, Ibandronic Acid Sandoz, Ibandronic Acid Teva
Drug Type
Small Molecule
Chemical Formula
C9H23NO7P2
CAS Number
114084-78-5
Unique Ingredient Identifier
UMD7G2653W
Background

Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid. It is used to prevent and treat postmenopausal osteoporosis. Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.
...

Indication

For the treatment and prevention of osteoporosis in postmenopausal women.

Associated Conditions
Bone Metastases, Hypercalcemia of Malignancy, Osteoporosis
Associated Therapies
-

Safety and Efficacy Study of Intravenous Loading Dose of Ibandronate in Breast Cancer Patients

Phase 2
Conditions
First Posted Date
2006-09-27
Last Posted Date
2006-12-04
Lead Sponsor
University of Turku
Target Recruit Count
60
Registration Number
NCT00381368
Locations
🇫🇮

Dept of Oncology, Helsinki University Central Hospital, Helsinki, Finland

🇫🇮

Dept of Oncology, Tampere University Hospital, Tampere, Finland

🇫🇮

Dept of Oncology, Oulu University Hospital, Oulu, Finland

Evaluation Of Missed Osteoporosis Diagnoses, And Preference Between Once Monthly Ibandronate And Once Weekly Alendronate

Phase 4
Completed
Conditions
First Posted Date
2006-05-19
Last Posted Date
2017-05-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
300
Registration Number
NCT00327990
Locations
🇳🇱

GSK Investigational Site, Zaandam, Netherlands

Study in Elderly Patients With Early Breast Cancer (ICE)

First Posted Date
2005-09-20
Last Posted Date
2014-07-17
Lead Sponsor
German Breast Group
Target Recruit Count
1500
Registration Number
NCT00196859
Locations
🇩🇪

Prof. Dr. med. Ulrike Nitz, Mönchengladbach, Nordrhein-Westfalen, Germany

A Study To Assess the Quality and Strength of Bone in Women Participants With Osteoporosis Taking Oral Ibandronate Versus Placebo

Phase 4
Completed
Conditions
Interventions
First Posted Date
2005-09-08
Last Posted Date
2016-11-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
98
Registration Number
NCT00148915
Locations
🇺🇸

GSK Investigational Site, Duncansville, Pennsylvania, United States

Study of Investigational Drug in Osteoporosis (MK-0217-908)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2004-09-24
Last Posted Date
2022-02-02
Lead Sponsor
Organon and Co
Target Recruit Count
203
Registration Number
NCT00092053
© Copyright 2024. All Rights Reserved by MedPath