Rabeprazole
- Generic Name
- Rabeprazole
- Brand Names
- Aciphex, Pariet
- Drug Type
- Small Molecule
- Chemical Formula
- C18H21N3O3S
- CAS Number
- 117976-89-3
- Unique Ingredient Identifier
- 32828355LL
Overview
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Background
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Indication
For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
Associated Conditions
- Duodenal Ulcer
- Gastric Ulcer
- Gastro-esophageal Reflux Disease (GERD)
- Heartburn
- Helicobacter Pylori Infection
- Non-erosive Reflux Esophagitis Disease (NERD)
- Vomiting
- Zollinger-Ellison Syndrome
- Develop NSAID-induced gastric ulcers
- Erosive reflux esophagitis
Clinical Trials
FDA Approved Products
Singapore Approved Products
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