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MT-0169

Generic Name
MT-0169
Drug Type
Biotech
Background

MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human single chain variable fragment with affinity for human CD38 cell surface protein.

Phase I Trial of MT-0169 in CD38+ Acute Leukemia With Relapsed/Refractory or Measurable Residual Disease

Phase 1
Withdrawn
Conditions
Leukemia
Interventions
First Posted Date
2024-07-26
Last Posted Date
2025-04-09
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
52
Registration Number
NCT06522373
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

A Study of MT-0169 in Participants With Relapsed or Refractory Multiple Myeloma

Phase 1
Terminated
Conditions
Relapsed and/or Refractory Multiple Myeloma
Interventions
First Posted Date
2019-07-12
Last Posted Date
2024-01-17
Lead Sponsor
Molecular Templates, Inc.
Target Recruit Count
14
Registration Number
NCT04017130
Locations
🇺🇸

The Ohio State University, Columbus, Ohio, United States

🇺🇸

Vanderbilt University Medical Center- Ingram Cancer Center, Nashville, Tennessee, United States

🇺🇸

Miami University, Miami, Florida, United States

and more 4 locations
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