MedPath

Glycerin

Generic Name
Glycerin
Brand Names
Clear Eyes Cooling Comfort, Clear Eyes Redness Relief Reformulated Nov 2011, Fleet Mineral Oil, Genteal Tears, Glycerolyte 57, Pedia-lax Liquid, Preparation H Cream, Procalamine 3, Refresh Optive Advanced, Refresh Optive Extended Therapy, Synovisol, Tears Lubricant
Drug Type
Small Molecule
Chemical Formula
C3H8O3
CAS Number
56-81-5
Unique Ingredient Identifier
PDC6A3C0OX
Background

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

Indication

It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.

Associated Conditions
Cold Sore, Constipation, Dry Mouth, Dry Skin, Dry throat, Edema of the cerebrum, Increase in Intracranial Pressure (ICP), Occasional Constipation, Ocular Discomfort, Ocular Hypertension, Ocular Irritation, Skin Infections, Sore Throat, Mouth soreness, Sensation of burning in the eyes
Associated Therapies
Bowel preparation therapy, Topical Antisepsis, Skin protection

Effectiveness of Topical Glycerine Sulphate Paste, Hirudoid Cream and Nil Application on Superficial Phlebitis

Not Applicable
Completed
Conditions
Infection
Interventions
First Posted Date
2010-10-21
Last Posted Date
2010-10-21
Lead Sponsor
Tan Tock Seng Hospital
Target Recruit Count
147
Registration Number
NCT01226069
Locations
🇸🇬

Tan Tock Seng Hospital, Singapore, Singapore

Dermacyd in Odor Reducing.

Phase 3
Completed
Conditions
Hygiene
Interventions
First Posted Date
2010-07-08
Last Posted Date
2011-01-04
Lead Sponsor
Sanofi
Target Recruit Count
230
Registration Number
NCT01158365
Locations
🇧🇷

Sanofi-Aventis Investigational Site Number 076-001, Osasco, Brazil

Comparative Safety and Efficacy Evaluation Between Dermacyd Silver and Glycerine Vegetal Soap Granado Traditional

Phase 3
Completed
Conditions
Hygiene
Interventions
Drug: Dermacid Silver (Lactic acid)
First Posted Date
2010-05-19
Last Posted Date
2010-12-02
Lead Sponsor
Sanofi
Target Recruit Count
70
Registration Number
NCT01126606
Locations
🇧🇷

Sanofi-Aventis Administrative Office, Sao Paulo, Brazil

Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects

Not Applicable
Completed
Conditions
Dry Eye Syndrome
Interventions
First Posted Date
2009-11-10
Last Posted Date
2015-08-17
Lead Sponsor
Allergan
Target Recruit Count
288
Registration Number
NCT01010282

Safety and Tolerability of Artificial Tears in Dry Eye Subjects

Not Applicable
Completed
Conditions
Dry Eye Syndrome
Interventions
First Posted Date
2009-07-03
Last Posted Date
2015-08-26
Lead Sponsor
Allergan
Target Recruit Count
47
Registration Number
NCT00932477

Idiopathic Hypertensive Anal Canal: a Place of Internal Sphincterotomy

Not Applicable
Completed
Conditions
Hypertensive Anal Canal
Interventions
Procedure: lateral internal sphincterotomy (LIS)
Drug: botulinum toxin injection (BTX A)
First Posted Date
2009-06-25
Last Posted Date
2009-06-25
Lead Sponsor
Mansoura University
Target Recruit Count
63
Registration Number
NCT00927849
Locations
🇪🇬

Ayman Elnakeeb, Mansoura, Egypt

Training Effects on Skeletal Muscle Fatty Acid Metabolism

Not Applicable
Completed
Conditions
Healthy Volunteers
Interventions
Drug: 20% lipid infusion
First Posted Date
2008-11-06
Last Posted Date
2015-07-23
Lead Sponsor
University of Minnesota
Target Recruit Count
33
Registration Number
NCT00786487
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation

Phase 4
Conditions
Dermatitis, Contact
Dermatitis, Occupational
First Posted Date
2008-10-24
Last Posted Date
2008-10-24
Lead Sponsor
Odense University Hospital
Target Recruit Count
36
Registration Number
NCT00779792
Locations
🇩🇰

Department of Dermatology, Odense University Hospital, Odense, Denmark

Tear Film Break-up Time After Instillation of Artificial Tears

Not Applicable
Completed
Conditions
Keratoconjunctivitis Sicca
Interventions
First Posted Date
2008-05-21
Last Posted Date
2012-10-26
Lead Sponsor
Calm Water Therapeutics LLC
Target Recruit Count
16
Registration Number
NCT00681265
Locations
🇺🇸

University of Rochester Eye Institute, Rochester, New York, United States

Oral Glycerol and High-Dose Rectal Paracetamol to Improve the Prognosis of Childhood Bacterial Meningitis

Phase 3
Completed
Conditions
Bacterial Meningitis
Interventions
First Posted Date
2008-02-20
Last Posted Date
2012-07-10
Lead Sponsor
Kamuzu University of Health Sciences
Target Recruit Count
466
Registration Number
NCT00619203
Locations
🇲🇼

College of Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi

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