Sertraline

Generic Name
Sertraline
Brand Names
Zoloft
Drug Type
Small Molecule
Chemical Formula
C17H17Cl2N
CAS Number
79617-96-2
Unique Ingredient Identifier
QUC7NX6WMB
Background

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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Indication

Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...

Associated Conditions
Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
Associated Therapies
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Integral Assessment in Unipolar Depression

Phase 4
Conditions
Interventions
First Posted Date
2014-10-20
Last Posted Date
2015-12-11
Lead Sponsor
University of Sao Paulo
Target Recruit Count
100
Registration Number
NCT02268487
Locations
🇧🇷

Insitute of Psychiatry of the University of São Paulo, São Paulo, Brazil

Optimizing Antidepressant Treatment by Genotype-dependent Adjustment of Medication According to the ABCB1 Gene

First Posted Date
2014-09-12
Last Posted Date
2014-09-12
Lead Sponsor
HolsboerMaschmeyer NeuroChemie GmbH
Target Recruit Count
80
Registration Number
NCT02237937
Locations
🇩🇪

Max Planck Institute of Psychiatry, Munich, Bavaria, Germany

Prophylactic Use of Postpartum Sertraline to Prevent Postpartum Depression

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2014-09-09
Last Posted Date
2018-03-29
Lead Sponsor
The Cooper Health System
Target Recruit Count
2
Registration Number
NCT02235064
Locations
🇺🇸

Cooper University Hospital, Camden, New Jersey, United States

The Effect of a Selective Serotonin Reuptake Inhibitor on Gait, Balance, and Bone Metabolism in Older Adults

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-08-28
Last Posted Date
2017-05-04
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
25
Registration Number
NCT02228005
Locations
🇨🇦

Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada

Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sleep

First Posted Date
2014-07-14
Last Posted Date
2021-10-11
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
14
Registration Number
NCT02189213
Locations
🇺🇸

NYSPI, New York, New York, United States

Effects and Consequences for Mother and Child From Treatment for Depression

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2014-07-09
Last Posted Date
2020-01-18
Lead Sponsor
Katarina Wide
Target Recruit Count
17
Registration Number
NCT02185547
Locations
🇸🇪

Karolinska University Hospital, Stockholm, Sweden

Antidepressants and Bone Mineral Density

First Posted Date
2014-07-01
Last Posted Date
2014-07-01
Lead Sponsor
Guiyang Medical University
Target Recruit Count
203
Registration Number
NCT02179268

Study of Drug Combination on Pharmacokinetics in Healthy Volunteers

First Posted Date
2014-06-26
Last Posted Date
2015-02-10
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
41
Registration Number
NCT02175602

A Randomised Trial of Sertraline, Cognitive Behaviour Therapy & Combined Therapy for Postnatal Depression

First Posted Date
2014-04-24
Last Posted Date
2014-04-29
Lead Sponsor
University of Melbourne
Target Recruit Count
45
Registration Number
NCT02122393
Locations
🇦🇺

Austin Health, Melbourne, Victoria, Australia

Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients

First Posted Date
2013-12-30
Last Posted Date
2022-09-09
Lead Sponsor
Shanghai Mental Health Center
Target Recruit Count
78
Registration Number
NCT02022709
Locations
🇨🇳

Shanghai Mental Health Center, Shanghai, Shanghai, China

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