Sertraline
- Generic Name
- Sertraline
- Brand Names
- Zoloft
- Drug Type
- Small Molecule
- Chemical Formula
- C17H17Cl2N
- CAS Number
- 79617-96-2
- Unique Ingredient Identifier
- QUC7NX6WMB
- Background
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
...
- Indication
Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...
- Associated Conditions
- Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
- Associated Therapies
- -
The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy
- Conditions
- Interventions
- First Posted Date
- 2012-04-03
- Last Posted Date
- 2015-03-04
- Lead Sponsor
- Charlotte Sonne
- Target Recruit Count
- 207
- Registration Number
- NCT01569685
- Locations
- 🇩🇰
Competence Center for Transcultural Psychiatry, Gentofte, Denmark
PROlonGed ExpoSure Sertraline
- Conditions
- Interventions
- First Posted Date
- 2012-02-01
- Last Posted Date
- 2018-02-28
- Lead Sponsor
- VA Ann Arbor Healthcare System
- Target Recruit Count
- 223
- Registration Number
- NCT01524133
- Locations
- 🇺🇸
Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, United States
🇺🇸VA San Diego Healthcare System, San Diego, California, United States
🇺🇸Ralph H. Johnson VA Medical Center/Savannah Primary Care Clinic, Savannah, Georgia, United States
Trial of Sertraline to Treat Children With Fragile X Syndrome
- First Posted Date
- 2011-11-18
- Last Posted Date
- 2017-09-25
- Lead Sponsor
- Randi J. Hagerman, MD
- Target Recruit Count
- 57
- Registration Number
- NCT01474746
- Locations
- 🇺🇸
UC Davis M.I.N.D. Institute, Sacramento, California, United States
Analisis of Facors Involved in Antidepressant Treatment Response of Major Depressive Disorder
- First Posted Date
- 2011-10-19
- Last Posted Date
- 2011-10-31
- Lead Sponsor
- Showa University
- Target Recruit Count
- 96
- Registration Number
- NCT01454635
- Locations
- 🇯🇵
Showa University Northern Yokohama Hospital, Yokohama, Kanagawa, Japan
The Effects of Sertraline on Depression in Parkinson's Disease
- First Posted Date
- 2011-09-20
- Last Posted Date
- 2024-01-30
- Lead Sponsor
- Zhejiang University
- Target Recruit Count
- 35
- Registration Number
- NCT01437189
- Locations
- 🇨🇳
Department of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care for Depression
- First Posted Date
- 2011-08-01
- Last Posted Date
- 2018-12-26
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 296
- Registration Number
- NCT01407094
- Locations
- 🇺🇸
Columbia Univerisity New York City, New York, New York, United States
🇺🇸University of Michigan Ann Arbor, Ann Arbor, Michigan, United States
🇺🇸Massachusetts General Hospital Boston, Boston, Massachusetts, United States
Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)
- First Posted Date
- 2011-05-26
- Last Posted Date
- 2018-09-17
- Target Recruit Count
- 2944
- Registration Number
- NCT01360866
- Locations
- 🇺🇦
Research Site, Poltava, Ukraine
Does Pregabalin Improve Symptoms of Anxiety in Patients With Epilepsy? A Comparison With Sertraline
- First Posted Date
- 2011-03-04
- Last Posted Date
- 2023-02-02
- Lead Sponsor
- Rush University Medical Center
- Registration Number
- NCT01309074
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
The Effect of Problem Solving Therapy and Antidepressant Therapy on Cerebral Perfusion and Brain Derived Neurotropic Factor (BDNF) in Depressed Elders
- Conditions
- Interventions
- First Posted Date
- 2011-03-01
- Last Posted Date
- 2022-05-26
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 19
- Registration Number
- NCT01305889
- Locations
- 🇺🇸
Langley Porter Psychiatric Institute, San Francisco, California, United States
Sertraline Pediatric Registry for the Evaluation of Safety (SPRITES)
- Conditions
- Interventions
- First Posted Date
- 2011-02-23
- Last Posted Date
- 2021-10-14
- Target Recruit Count
- 941
- Registration Number
- NCT01302080
- Locations
- 🇺🇸
Harmonex Neuroscience Research, Dothan, Alabama, United States
🇺🇸Family Behavioral Health, Plainfield, Illinois, United States
🇺🇸University of South Florida - Rothman Center, Saint Petersburg, Florida, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.