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Aminocaproic acid

Generic Name
Aminocaproic acid
Brand Names
Amicar
Drug Type
Small Molecule
Chemical Formula
C6H13NO2
CAS Number
60-32-2
Unique Ingredient Identifier
U6F3787206
Background

An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

Indication

For use in the treatment of excessive postoperative bleeding.

Associated Conditions
Hemorrhage

Tranexamic Acid (TXA) Versus Epsilon Aminocaproic Acid (EACA) Versus Placebo for Spine Surgery

Phase 4
Completed
Conditions
Scoliosis
Interventions
First Posted Date
2009-08-13
Last Posted Date
2018-01-17
Lead Sponsor
NYU Langone Health
Target Recruit Count
177
Registration Number
NCT00958581
Locations
🇺🇸

New York University School of Medicine - Department of Orthopaedic Surgery - Spine, New York, New York, United States

Amicar Pharmacokinetics of Children Having Craniofacial Surgery

Phase 1
Completed
Conditions
Craniosynostosis
Interventions
First Posted Date
2009-06-03
Last Posted Date
2012-11-01
Lead Sponsor
Paul Stricker
Target Recruit Count
18
Registration Number
NCT00912119
Locations
🇺🇸

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Effects of Aprotinin During Cardiac Surgery/Long Term Death Rates

Completed
Conditions
Cardiac Surgery
Interventions
First Posted Date
2008-02-18
Last Posted Date
2016-04-19
Lead Sponsor
State University of New York - Upstate Medical University
Target Recruit Count
462
Registration Number
NCT00617955
Locations
🇺🇸

SUNY Upstate Medical University, Syracuse, New York, United States

Bradykinin Receptor Antagonism During Cardiopulmonary Bypass

Phase 2
Completed
Conditions
Fibrinolysis
Cardiopulmonary Bypass
Inflammation
Surgery
Interventions
First Posted Date
2005-09-22
Last Posted Date
2013-11-25
Lead Sponsor
Vanderbilt University
Target Recruit Count
150
Registration Number
NCT00223704
Locations
🇺🇸

TN Valley Healthcare System, Nashville, Tennessee, United States

🇺🇸

Vanderbilt University, Nashville, Tennessee, United States

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