Aminocaproic acid

Generic Name
Aminocaproic acid
Brand Names
Amicar
Drug Type
Small Molecule
Chemical Formula
C6H13NO2
CAS Number
60-32-2
Unique Ingredient Identifier
U6F3787206
Background

An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

Indication

For use in the treatment of excessive postoperative bleeding.

Associated Conditions
Hemorrhage
Associated Therapies
-

Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation

First Posted Date
2021-03-24
Last Posted Date
2024-06-26
Lead Sponsor
NYU Langone Health
Target Recruit Count
46
Registration Number
NCT04814433
Locations
🇺🇸

NYU Langone Health, New York, New York, United States

Activated Factor Seven in Traumatic Retro Peritoneal Hematoma

First Posted Date
2020-06-11
Last Posted Date
2020-06-11
Lead Sponsor
King Abdul Aziz Specialist Hospital
Target Recruit Count
80
Registration Number
NCT04424563
Locations
🇸🇦

King abd el Aziz specialist hospital, Ta'if, Saudi Arabia

A Pilot Study Comparing Anti-Inflammatory Effects Of TXA Versus EACA In Pediatric Congenital Heart Surgery

First Posted Date
2016-01-15
Last Posted Date
2024-10-24
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
22
Registration Number
NCT02656472
Locations
🇺🇸

Advocate Childrens Hospital, Oak Lawn, Illinois, United States

Randomized Clinical Trial With Aminocaproic Acid in the Prevention of Exodontic Bleeding in Anticoagulants Patients

First Posted Date
2014-09-12
Last Posted Date
2014-09-12
Lead Sponsor
Grupo de Estudos Multicentricos em Onco-Hematologia
Target Recruit Count
154
Registration Number
NCT02238288
Locations
🇧🇷

Clementino Fraga Filho University Hospital, Rio de Janeiro, RJ, Brazil

PRevention Of BLeeding in hEmatological Malignancies With Antifibrinolytic (Epsilon Aminocaproic Acid)

First Posted Date
2014-02-28
Last Posted Date
2022-07-19
Lead Sponsor
Emory University
Target Recruit Count
29
Registration Number
NCT02074436
Locations
🇺🇸

Atlanta VA Medical Center, Decatur, Georgia, United States

🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

TXA vs. Amicar in Total Knee and Hip Arthroplasty

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-01-09
Last Posted Date
2018-12-05
Lead Sponsor
Duke University
Target Recruit Count
246
Registration Number
NCT02030821
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Comparison of Tranexamic to Epsilon Aminocaproic Acid: a Prospective Analysis of Blood Conservation in Cardiac Surgery

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-11-25
Last Posted Date
2020-10-19
Lead Sponsor
Loma Linda University
Target Recruit Count
100
Registration Number
NCT01248104
Locations
🇺🇸

Loma Linda University Medical Center, Loma Linda, California, United States

Tranexamic Acid (TXA) Versus Epsilon Aminocaproic Acid (EACA) Versus Placebo for Spine Surgery

First Posted Date
2009-08-13
Last Posted Date
2018-01-17
Lead Sponsor
NYU Langone Health
Target Recruit Count
177
Registration Number
NCT00958581
Locations
🇺🇸

New York University School of Medicine - Department of Orthopaedic Surgery - Spine, New York, New York, United States

Amicar Pharmacokinetics of Children Having Craniofacial Surgery

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-06-03
Last Posted Date
2012-11-01
Lead Sponsor
Paul Stricker
Target Recruit Count
18
Registration Number
NCT00912119
Locations
🇺🇸

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

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