Aminocaproic acid

Generic Name: Aminocaproic acid

Brand Names: Amicar

Drug Type: Small Molecule

Chemical Formula: C_₆H_₁₃NO_₂

CAS Number: 60-32-2

Unique Ingredient Identifier: U6F3787206

Background: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

Indication: For use in the treatment of excessive postoperative bleeding.

Associated Conditions: Hemorrhage

Associated Therapies: -

Clinical Trials

Effects of Aprotinin During Cardiac Surgery/Long Term Death Rates

Completed

Conditions: Cardiac Surgery

Interventions: Drug: Aprotinin
Drug: Amicar

First Posted Date: 2008-02-18

Last Posted Date: 2016-04-19

Lead Sponsor: State University of New York - Upstate Medical University

Target Recruit Count: 462

Registration Number: NCT00617955

Locations: 🇺🇸
SUNY Upstate Medical University, Syracuse, New York, United States

Bradykinin Receptor Antagonism During Cardiopulmonary Bypass

Phase 2

Completed

Conditions: Fibrinolysis
Cardiopulmonary Bypass
Inflammation
Surgery

Interventions: Drug: HOE 140
Drug: Aminocaproic Acid
Drug: Placebo

First Posted Date: 2005-09-22

Last Posted Date: 2013-11-25

Lead Sponsor: Vanderbilt University

Target Recruit Count: 150

Registration Number: NCT00223704

Locations: 🇺🇸
TN Valley Healthcare System, Nashville, Tennessee, United States
🇺🇸
Vanderbilt University, Nashville, Tennessee, United States

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