Sugammadex

Generic Name
Sugammadex
Brand Names
Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal
Drug Type
Small Molecule
Chemical Formula
C72H112O48S8
CAS Number
343306-71-8
Unique Ingredient Identifier
361LPM2T56
Background

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intuba...

Indication

Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide in adults and pediatric patients ≥2 years old who are undergoing surgery.

Associated Conditions
Neuromuscular blockade caused by vecuronium bromide
Associated Therapies
-
Clinical Trials
Related News

Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery Profile

First Posted Date
2014-09-18
Last Posted Date
2017-02-06
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
100
Registration Number
NCT02243943
Locations
🇳🇱

Leiden Medical University, Leiden, Zuid Holland, Netherlands

Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular Blockade

First Posted Date
2014-08-13
Last Posted Date
2015-04-21
Lead Sponsor
T.C. ORDU ÜNİVERSİTESİ
Target Recruit Count
36
Registration Number
NCT02215382
Locations
🇹🇷

Anesthesiology and Reanimation Dept. Ordu University Training and Research Hospital, Altınordu, Ordu, Turkey

Sugammadex Compared With Neostigmin/Atropin for Neuromuscular Block Reversal in Patients With Obstructive Sleep Apnea

Phase 4
Completed
Conditions
Obstructive Sleep Apnea
Interventions
Drug: Neostigmine
Drug: Sugammadex
First Posted Date
2014-06-10
Last Posted Date
2014-12-09
Lead Sponsor
Diskapi Teaching and Research Hospital
Target Recruit Count
74
Registration Number
NCT02160223
Locations
🇹🇷

Diskapi Yildirim Beyazit Teaching and Research Hospital, Ankara, Turkey

A Pilot Study Using Rocuronium to Prevent Intermediate Syndrome After Organophosphorus Insecticide Poisoning

Phase 2
Completed
Conditions
Organophosphate Poisoning
Interventions
Drug: Rocuronium
Drug: Sugammadex
First Posted Date
2014-05-26
Last Posted Date
2016-11-17
Lead Sponsor
University of Edinburgh
Target Recruit Count
45
Registration Number
NCT02147054
Locations
🇱🇰

Peradeniya Teaching Hospital, Peradeniya, Central Province, Sri Lanka

The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy

First Posted Date
2014-04-09
Last Posted Date
2015-06-24
Lead Sponsor
Yonsei University
Target Recruit Count
67
Registration Number
NCT02109133
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of

Validation of Subjective Rating Scales Used to Assess Surgical Conditions in Abdominal Surgery

First Posted Date
2014-03-05
Last Posted Date
2014-07-09
Lead Sponsor
Herlev Hospital
Target Recruit Count
14
Registration Number
NCT02079337
Locations
🇩🇰

Department of minimal invasive gynecology Aleris-Hamlet Private Hospital, Søborg, Denmark

A Study to Evaluate the Incidence of Hypersensitivity After Administration of Sugammadex in Healthy Participants (MK-8616-101)

Phase 1
Completed
Conditions
Anaphylaxis
Hypersensitivity
Interventions
Drug: Placebo
Drug: Sugammadex
First Posted Date
2014-01-06
Last Posted Date
2019-04-03
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
382
Registration Number
NCT02028065

Pharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105)

Phase 1
Completed
Conditions
Renal Impairment
Renal Insufficiency
Interventions
Drug: sugammadex
First Posted Date
2013-12-13
Last Posted Date
2018-10-02
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
33
Registration Number
NCT02011490
Locations
🇺🇸

Investigational Site 001, Hialeah, Florida, United States

A Double-blind, Randomized, Parallel Design Study to Compare the Effectiveness of Sugammadex Versus Neostigmine in Improving Surgical Condition in Subjects Undergoing Laryngeal Microsurgery

Not Applicable
Completed
Conditions
General Anesthesia
Interventions
Drug: Neostigmine
Drug: Sugammadex
First Posted Date
2013-11-08
Last Posted Date
2015-04-23
Lead Sponsor
Yonsei University
Target Recruit Count
72
Registration Number
NCT01980069
Locations
🇰🇷

Severance Hospital, Seoul, Seodaemun-gu, Korea, Republic of

Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients

First Posted Date
2013-10-30
Last Posted Date
2014-02-25
Lead Sponsor
Kocaeli University
Target Recruit Count
80
Registration Number
NCT01972659
Locations
🇹🇷

Kocaeli University Hospital, Kocaeli, Turkey

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy