NCT02215382已完成4 期
Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular Blockade
T.C. ORDU ÜNİVERSİTESİ1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2014年8月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- intraocular pressure
研究概览
简要总结
The aim of this study, comparison of effects of sugammadex versus neostigmine/atropine combination on hemodynamic parameters and intraocular pressure during tracheal extubation.
This prospective, randomised study was designed to compare two reversal methods with respect to changes in IOP, heart rate and blood pressure during tracheal extubation period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-II physical status
- •elective surgery
- •endotracheal intubation under general anesthesia
排除标准
- •emergency surgery
- •pregnancy
- •laparoscopic surgery
- •prone position
- •BMI > 30 kg/m2
- •sedative drug use in last month
- •patients with glaucoma.
- •ASA > II physical status
研究组 & 干预措施
sugammadex
Active Comparator
干预措施: sugammadex (Drug)
neostigmine + atropine
Active Comparator
干预措施: neostigmine+atropine (Drug)
结局指标
主要结局
intraocular pressure
时间窗: baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation
次要结局
- blood pressure(baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation)
- heart rate(baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation)
研究者
özgür yağan
MD, assistant professor
T.C. ORDU ÜNİVERSİTESİ
研究点 (1)
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