Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular Blockade
Phase 4
Completed
- Conditions
- Intraocular Pressure Changes During Tracheal Extubation
- Interventions
- Drug: neostigmine+atropine
- Registration Number
- NCT02215382
- Lead Sponsor
- T.C. ORDU ÜNİVERSİTESİ
- Brief Summary
The aim of this study, comparison of effects of sugammadex versus neostigmine/atropine combination on hemodynamic parameters and intraocular pressure during tracheal extubation.
This prospective, randomised study was designed to compare two reversal methods with respect to changes in IOP, heart rate and blood pressure during tracheal extubation period.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
- ASA I-II physical status
- elective surgery
- endotracheal intubation under general anesthesia
Exclusion Criteria
- emergency surgery
- pregnancy
- laparoscopic surgery
- prone position
- BMI > 30 kg/m2
- sedative drug use in last month
- patients with glaucoma.
- ASA > II physical status
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description sugammadex sugammadex - neostigmine + atropine neostigmine+atropine -
- Primary Outcome Measures
Name Time Method intraocular pressure baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation
- Secondary Outcome Measures
Name Time Method blood pressure baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation heart rate baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation
Trial Locations
- Locations (1)
Anesthesiology and Reanimation Dept. Ordu University Training and Research Hospital
🇹🇷Altınordu, Ordu, Turkey