Fluciclovine
- Generic Name
- Fluciclovine
- Drug Type
- Small Molecule
- Chemical Formula
- C5H8FNO2
- CAS Number
- 222727-43-7
- Unique Ingredient Identifier
- YKG0YF688X
- Background
Fluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery
- Conditions
- Brain Metastases, AdultBrain CancerBrain Metastases
- Interventions
- First Posted Date
- 2023-09-21
- Last Posted Date
- 2025-05-18
- Lead Sponsor
- Baptist Health South Florida
- Target Recruit Count
- 46
- Registration Number
- NCT06048094
- Locations
- 🇺🇸
Miami Cancer Institute, Miami, Florida, United States
Evaluating Fluciclovine PET in Patients With Biochemical Recurrence of Prostate Cancer and a Negative PSMA PET
- First Posted Date
- 2023-02-10
- Last Posted Date
- 2025-01-10
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 50
- Registration Number
- NCT05722925
- Locations
- 🇺🇸
Oregon Health & Science University, Portland, Oregon, United States
Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR
- Conditions
- Brain MetastasesGlioblastomaGliomasCancer
- Interventions
- Other: Standard of Care
- First Posted Date
- 2021-09-23
- Last Posted Date
- 2023-09-01
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT05054400
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Radiotherapy Planning Using Fluciclovine PET in Patients With Newly Diagnosed Glioblastoma
- Conditions
- Newly Diagnosed Glioblastoma
- Interventions
- First Posted Date
- 2021-04-09
- Last Posted Date
- 2023-01-13
- Lead Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
- Target Recruit Count
- 100
- Registration Number
- NCT04840069
- Locations
- 🇺🇸
St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery
- Conditions
- Brain CancerBrain MetastasesBrain Metastases, Adult
- Interventions
- First Posted Date
- 2020-12-30
- Last Posted Date
- 2025-01-17
- Lead Sponsor
- Baptist Health South Florida
- Target Recruit Count
- 20
- Registration Number
- NCT04689048
- Locations
- 🇺🇸
Miami Cancer Institute, Miami, Florida, United States
Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases (PURSUE)
- First Posted Date
- 2020-06-01
- Last Posted Date
- 2023-08-01
- Lead Sponsor
- Blue Earth Diagnostics
- Target Recruit Count
- 23
- Registration Number
- NCT04410367
- Locations
- 🇺🇸
University Hospital Cleveland, Cleveland, Ohio, United States
🇺🇸University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States
🇺🇸Miami Cancer Institute, Miami, Florida, United States
Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases
- First Posted Date
- 2020-06-01
- Last Posted Date
- 2023-07-12
- Lead Sponsor
- Blue Earth Diagnostics
- Target Recruit Count
- 151
- Registration Number
- NCT04410133
- Locations
- 🇺🇸
West Virgina University Cancer Institute, Morgantown, West Virginia, United States
🇺🇸Medical College of Georgia, Augusta University, Augusta, Georgia, United States
🇺🇸John Wayne Cancer Institute at Providence St. John's Health Center, Santa Monica, California, United States
Pilot Study to Assess the Potential Clinical Utility of 18F Fluciclovine PET for Cervical and Endometrial Cancer.
- Conditions
- Cervical CancerUterine Cancer
- Interventions
- Device: 18F fluciclovine PET
- First Posted Date
- 2018-02-06
- Last Posted Date
- 2020-10-28
- Lead Sponsor
- Nghi Nguyen
- Target Recruit Count
- 1
- Registration Number
- NCT03423082
- Locations
- 🇺🇸
UPMC Presbyterian - MR Research Center, Pittsburgh, Pennsylvania, United States
Pretreatment Staging of High-Risk Prostate Cancer With 18F-Fluciclovine PET/MRI
- Conditions
- Prostate Cancer
- Interventions
- Diagnostic Test: [18F] Fluciclovine PET/MRI
- First Posted Date
- 2017-08-29
- Last Posted Date
- 2020-03-09
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 18
- Registration Number
- NCT03264456
- Locations
- 🇺🇸
University of Alabama at Birmingham Medical Center, Birmingham, Alabama, United States
Drug Development Updates
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