Doxofylline

Generic Name
Doxofylline
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C11H14N4O4
CAS Number
69975-86-6
Unique Ingredient Identifier
MPM23GMO7Z
Background

Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does not significantly bind to adenos...

Indication

Indicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.

Associated Conditions
Bronchial Asthma, Chronic Obstructive Pulmonary Disease (COPD), Lung Disorder
Associated Therapies
-

Bronchodilator Effect of Oral Doxofylline and Procaterol in Chronic Obstructive Pulmonary Disease

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-04-04
Last Posted Date
2024-04-05
Lead Sponsor
Thammasat University
Target Recruit Count
20
Registration Number
NCT06346691

Effect of add-on Doxofylline on Lung Function in Stable COPD

First Posted Date
2020-01-23
Last Posted Date
2020-03-30
Lead Sponsor
University of Milan
Target Recruit Count
78
Registration Number
NCT04238221
Locations
🇮🇹

L. Sacco Hospital, Milan, Italy

Efficacy Of Doxophylline As A Sparing Treatment For Inhaled Corticosteroids In Mexican Children With Asthma

First Posted Date
2019-03-19
Last Posted Date
2019-03-19
Lead Sponsor
Universidad Autonoma de Nuevo Leon
Target Recruit Count
60
Registration Number
NCT03879590
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