Danazol
- Generic Name
- Danazol
- Brand Names
- Cyclomen
- Drug Type
- Small Molecule
- Chemical Formula
- C22H27NO2
- CAS Number
- 17230-88-5
- Unique Ingredient Identifier
- N29QWW3BUO
- Background
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
- Indication
For the treatment of endometriosis and fibrocystic breast disease (in patients unresponsive to simple measures). Also used for the prophylactic treatment of all types of hereditary angioedema in males and females.
- Associated Conditions
- Endometriosis, Fibrocystic Disease of Breast, Hereditary Angioedema (HAE), Refractory immune thrombocytopenia
A Study of Topical Danazol for the Treatment of Pain Associated With Fibrocystic Breast Disease
- First Posted Date
- 2008-08-29
- Last Posted Date
- 2010-05-27
- Lead Sponsor
- FemmePharma Global Healthcare, Inc.
- Target Recruit Count
- 60
- Registration Number
- NCT00744276
- Locations
- 🇺🇸
Columbus Center for Women's Health Research, Columbus, Ohio, United States
🇺🇸Palm Beach Research Center, West Palm Beach, Florida, United States
🇺🇸James A Simon, M.D., PC, Washington, District of Columbia, United States
Danazol in Treating Patients With Advanced or Recurrent Endometrial Cancer
- Conditions
- Endometrial Cancer
- First Posted Date
- 2004-06-25
- Last Posted Date
- 2013-06-10
- Lead Sponsor
- Gynecologic Oncology Group
- Registration Number
- NCT00003946
- Locations
- 🇺🇸
Johns Hopkins Oncology Center, Baltimore, Maryland, United States
🇺🇸USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States
🇺🇸Kimmel Cancer Center of Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States
Drug Development Updates
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