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MK-2206

Generic Name
MK-2206
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C25H21N5O
CAS Number
1032349-93-1
Unique Ingredient Identifier
51HZG6MP1K
Associated Conditions
-
Associated Therapies
-

Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney Cancer

Phase 2
Terminated
Conditions
Metastatic Kidney Carcinoma
Recurrent Renal Cell Carcinoma
Stage IV Renal Cell Cancer AJCC v7
Stage III Renal Cell Cancer AJCC v7
Interventions
Drug: Akt Inhibitor MK2206
Drug: Everolimus
Other: Laboratory Biomarker Analysis
First Posted Date
2010-11-11
Last Posted Date
2019-10-10
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
43
Registration Number
NCT01239342
Locations
🇺🇸

USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

🇺🇸

Tower Cancer Research Foundation, Beverly Hills, California, United States

🇺🇸

University of California Davis Comprehensive Cancer Center, Sacramento, California, United States

and more 5 locations

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Phase 1
Completed
Conditions
Accelerated Phase Chronic Myelogenous Leukemia
Acute Leukemias of Ambiguous Lineage
Acute Myeloid Leukemia/Transient Myeloproliferative Disorder
Acute Undifferentiated Leukemia
Aggressive NK-cell Leukemia
Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative
Blastic Phase Chronic Myelogenous Leukemia
Childhood Chronic Myelogenous Leukemia
Chronic Phase Chronic Myelogenous Leukemia
Mast Cell Leukemia
Interventions
Drug: Akt inhibitor MK2206
Other: diagnostic laboratory biomarker analysis
Other: pharmacological study
First Posted Date
2010-11-01
Last Posted Date
2014-04-29
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
45
Registration Number
NCT01231919
Locations
🇺🇸

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States

🇨🇦

Hospital for Sick Children, Toronto, Ontario, Canada

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

and more 22 locations
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