Bemiparin

Generic Name
Bemiparin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
91449-79-5
Unique Ingredient Identifier
PUE0TO3XDR
Background

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and act mainly on factor-Xa, reducing the risk of bleeding due to selectivity for this specific clotting factor. Interestingly, current research is underway for the potential benefit of bemiparin in the treatment of tumors and diabetic foot ulcers .

Indication

Bemiparin is indicated in the following cases: To prevent blood clots in the veins after general abdominal surgery in patients with a moderate risk of venous thromboembolism; in the prevention of the thromboembolic disease in non-surgical patients; prevention of clotting in the extracorporeal circuit during hemodialysis; to prevent blood clots in the veins after a major orthopedic surgery in patients with high risk of venous thromboembolism; secondary prevention of venous thromboembolism; recurrence in patients with deep vein thrombosis; transient prevention and treatment of deep vein thrombosis (DVT) .

Associated Conditions
Extracorporeal Clotting During Hemodialysis, Thromboembolism
Associated Therapies
Dialysis therapy

Study to Assess Bemiparin Pharmacokinetics in Renal Insufficiency and in the Elderly

Phase 1
Completed
Conditions
First Posted Date
2006-12-19
Last Posted Date
2011-03-18
Lead Sponsor
Rovi Pharmaceuticals Laboratories
Target Recruit Count
60
Registration Number
NCT00413088
Locations
🇪🇸

Hospital de la Santa Creu i Sant Pau and Fundació Puigvert, Barcelona, Spain

Adjuvant BEmiparin in Small Cell Lung Carcinoma (ABEL STUDY)

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2006-05-11
Last Posted Date
2012-06-08
Lead Sponsor
Clinica Universidad de Navarra, Universidad de Navarra
Target Recruit Count
39
Registration Number
NCT00324558
Locations
🇪🇸

Hospital de Sagunto, Puerto de Sagunto, Valencia, Spain

🇪🇸

Hospital Río Hortega, Valladolid, Spain

🇪🇸

Hospital de Cruces, Barakaldo, Vizcaya, Spain

and more 12 locations

Efficacy & Safety of Prophylaxis With Bemiparin in Cancer Patients With a Central Venous Catheter (BECAT)

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2006-04-06
Last Posted Date
2012-06-08
Lead Sponsor
Clinica Universidad de Navarra, Universidad de Navarra
Target Recruit Count
402
Registration Number
NCT00311896
Locations
🇷🇴

District Emergency Clinical Hospital, Targu-Mures, Romania

🇪🇸

Hospital Clínico San Carlos-Madrid., Madrid, Spain

🇪🇸

Hospital Santa Creu i Sant Pau, Barcelona, Spain

and more 16 locations

CANBESURE STUDY (Cancer, Bemiparin and Surgery Evaluation)

Phase 3
Completed
Conditions
First Posted Date
2005-09-22
Last Posted Date
2010-04-28
Lead Sponsor
Rovi Pharmaceuticals Laboratories
Target Recruit Count
526
Registration Number
NCT00219973
© Copyright 2024. All Rights Reserved by MedPath