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Pazopanib

Generic Name: Pazopanib

Brand Names: Votrient

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₃N_₇O_₂S

CAS Number: 444731-52-6

Unique Ingredient Identifier: 7RN5DR86CK

Overview

Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

Background

Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

Indication

Treatment of advanced renal cell cancer and advanced soft tissue sarcoma (in patients previously treated with chemotherapy)

Associated Conditions

Advanced Renal Cell Carcinoma
Advanced Soft Tissue Sarcoma
Advanced Thyroid cancer

Clinical Trials

Evaluation of Pazopanib on Bleeding in Subjects With Hereditary Haemorrhagic Telangiectasia

Phase 2

Terminated

Posted: 2014/07/30

Sponsor:GlaxoSmithKline

ID:NCT02204371

Pazopanib Vs. Pazopanib Plus Gemcitabine

Phase 2

Active, not recruiting

Posted: 2014/07/30

Sponsor:North Eastern German...

ID:NCT02203760

Pazopanib in Molecularly Selected Patients With Advanced NSCLC

Phase 2

Terminated

Posted: 2014/07/17

Sponsor:Washington Universit...

ID:NCT02193152

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Phase 2

Active, not recruiting

Posted: 2014/07/03

Sponsor:National Cancer Inst...

ID:NCT02180867

Pazopanib Tolerability When Given With Food

Phase 1

Completed

Posted: 2014/05/14

Sponsor:Radboud University M...

ID:NCT02138526

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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