Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

S0220: Chemoradiotherapy Followed By Surgery and Docetaxel in Treating Patients With Pancoast Tumors

First Posted Date
2003-06-06
Last Posted Date
2013-11-25
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
46
Registration Number
NCT00062439
Locations
🇺🇸

Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood, Illinois, United States

🇺🇸

Holland Community Hospital, Holland, Michigan, United States

🇺🇸

Providence Cancer Institute at Providence Hospital - Southfield Campus, Southfield, Michigan, United States

and more 150 locations

Neoadjuvant Chemoradiotherapy Followed By Surgery in Treating Patients With Limited-Stage Small Cell Lung Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-06-06
Last Posted Date
2010-02-12
Lead Sponsor
Fox Chase Cancer Center
Registration Number
NCT00062322
Locations
🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

Neoadjuvant Chemoradiotherapy With or Without Gefitinib in Treating Patients With Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-06-06
Last Posted Date
2015-10-08
Lead Sponsor
University of Alabama at Birmingham
Registration Number
NCT00062270
Locations
🇺🇸

University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States

Cisplatin Combined With Radiation Therapy and Hyperthermia in Treating Patients With Stage II, Stage III, or Stage IV Cervical Cancer

Phase 2
Conditions
First Posted Date
2003-06-05
Last Posted Date
2013-08-07
Lead Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Registration Number
NCT00008112
Locations
🇳🇱

Academisch Medisch Centrum, Amsterdam, Netherlands

🇳🇱

University Hospital - Rotterdam Dijkzigt, Rotterdam, Netherlands

🇳🇱

Rotterdam Cancer Institute, Rotterdam, Netherlands

and more 1 locations

UCN-01 and Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors

First Posted Date
2003-05-30
Last Posted Date
2010-01-15
Lead Sponsor
City of Hope Medical Center
Registration Number
NCT00006464
Locations
🇺🇸

City of Hope Medical Group, Pasadena, California, United States

🇺🇸

Norris Cotton Cancer Center, Lebanon, New Hampshire, United States

🇺🇸

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

and more 1 locations

Docetaxel and Cisplatin in Treating Patients With Untreated Stage IIIA Non-small Cell Lung Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-05-21
Last Posted Date
2012-07-18
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
47
Registration Number
NCT00005868
Locations
🇳🇱

Leiden University Medical Center, Leiden, Netherlands

🇮🇹

Istituto Nazionale per la Ricerca sul Cancro, Genoa (Genova), Italy

🇳🇱

Groot Ziekengasthuis 's-Hertogenbosch, 's-Hertogenbosch, Netherlands

and more 20 locations

Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors

First Posted Date
2003-05-19
Last Posted Date
2013-08-23
Lead Sponsor
Children's Oncology Group
Target Recruit Count
168
Registration Number
NCT00003203
Locations
🇺🇸

Children's National Medical Center, Washington, District of Columbia, United States

🇺🇸

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States

🇨🇦

British Columbia Children's Hospital, Vancouver, British Columbia, Canada

and more 35 locations

Combination Chemotherapy in Treating Patients With Stage IV Locally Advanced or Metastatic Bladder Cancer

First Posted Date
2003-05-16
Last Posted Date
2013-09-05
Lead Sponsor
University of Chicago
Target Recruit Count
6
Registration Number
NCT00005086
Locations
🇺🇸

Louis A. Weiss Memorial Hospital, Chicago, Illinois, United States

🇺🇸

Fort Wayne Medical Oncology and Hematology, Inc., Fort Wayne, Indiana, United States

🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

and more 1 locations

Chemotherapy Combined With Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

First Posted Date
2003-05-07
Last Posted Date
2015-11-17
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
36
Registration Number
NCT00059761
Locations
🇺🇸

Ellis Fischel Cancer Center at University of Missouri - Columbia, Columbia, Missouri, United States

🇺🇸

Albert Einstein Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

University of Florida Shands Cancer Center, Gainesville, Florida, United States

and more 46 locations
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