Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

First Posted Date
2003-02-06
Last Posted Date
2014-06-24
Lead Sponsor
University of Leicester
Target Recruit Count
316
Registration Number
NCT00053872
Locations
🇫🇷

Institut Curie Hopital, Paris, France

🇩🇪

Universitaets - Kinderklinik Wuerzburg, Wuerzburg, Germany

🇳🇱

Academisch Medisch Centrum at University of Amsterdam, Amsterdam, Netherlands

and more 5 locations

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

Phase 1
Conditions
First Posted Date
2003-01-28
Last Posted Date
2009-07-07
Lead Sponsor
Theradex
Registration Number
NCT00053105
Locations
🇺🇸

Arizona Clinical Research Center, Tucson, Arizona, United States

🇺🇸

Highlands Oncology Group, Springdale, Arkansas, United States

🇺🇸

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

and more 4 locations

Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors

First Posted Date
2003-01-28
Last Posted Date
2021-07-13
Lead Sponsor
Children's Oncology Group
Target Recruit Count
302
Registration Number
NCT00053352
Locations
🇺🇸

West Virginia University Charleston, Charleston, West Virginia, United States

🇺🇸

Geisinger Medical Center, Danville, Pennsylvania, United States

🇺🇸

Children's Hospital Central California, Madera, California, United States

and more 123 locations

S0124: Cisplatin Combined With Irinotecan or Etoposide For Extensive-Stage Small Cell Lung Cancer

First Posted Date
2003-01-27
Last Posted Date
2018-07-31
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
671
Registration Number
NCT00045162
Locations
🇺🇸

Northside Hospital Cancer Center, Atlanta, Georgia, United States

🇺🇸

Saint Joseph's Hospital of Atlanta, Atlanta, Georgia, United States

🇺🇸

MetroHealth's Cancer Care Center at MetroHealth Medical Center, Cleveland, Ohio, United States

and more 399 locations

Comparison of Two Combination Chemotherapy Regimens in Treating Non-small Cell Lung Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2023-06-15
Lead Sponsor
Eastern Cooperative Oncology Group
Registration Number
NCT00006004
Locations
🇵🇪

Instituto de Enfermedades Neoplasicas, Lima, Peru

🇺🇸

Mercy Medical Center, Des Moines, Iowa, United States

🇺🇸

Iowa Methodist Medical Center, Des Moines, Iowa, United States

and more 13 locations

Platinum-based Chemotherapy With or Without Paclitaxel in Treating Patients With Relapsed Ovarian Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-12-19
Lead Sponsor
Medical Research Council
Target Recruit Count
800
Registration Number
NCT00002894
Locations
🇬🇧

Middlesex Hospital- Meyerstein Institute, London, England, United Kingdom

Radiation Therapy Alone Compared to Radiation Therapy Plus Chemotherapy in Treating Patients With Previously Untreated Cancer of the Nasopharynx

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-19
Lead Sponsor
National Cancer Centre, Singapore
Target Recruit Count
200
Registration Number
NCT00003637
Locations
🇸🇬

National Cancer Centre - Singapore, Singapore, Singapore

Surgery With or Without Combination Chemotherapy in Treating Patients With Stomach Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-19
Lead Sponsor
Medical Research Council
Target Recruit Count
500
Registration Number
NCT00002615
Locations
🇬🇧

Epsom General Hospital, Epsom, Surrey, United Kingdom

Chemotherapy in Treating Patients With Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

Phase 2
Terminated
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
3
Registration Number
NCT00014313
Locations
🇬🇧

Institute of Cancer Research - UK, Sutton, England, United Kingdom

© Copyright 2024. All Rights Reserved by MedPath