Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Combination Chemotherapy in Treating Patients With Advanced Ovarian Epithelial Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2012-11-09
Lead Sponsor
NYU Langone Health
Registration Number
NCT00005051
Locations
🇺🇸

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States

🇺🇸

Saint Vincent Catholic Medical Center of New York, New York, New York, United States

🇺🇸

New York Hospital Medical Center of Queens, Fresh Meadows, New York, United States

and more 7 locations

Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-07-19
Lead Sponsor
Radiation Therapy Oncology Group
Registration Number
NCT00009880
Locations
🇺🇸

Memorial Hospital of South Bend, South Bend, Indiana, United States

🇺🇸

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, United States

🇺🇸

Mount Carmel West Hospital, Columbus, Ohio, United States

and more 63 locations

Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-07-18
Lead Sponsor
Children's Hospital Los Angeles
Registration Number
NCT00006258
Locations
🇺🇸

Geisinger Medical Center, Danville, Pennsylvania, United States

🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇨🇦

Tom Baker Cancer Centre - Calgary, Calgary, Alberta, Canada

7-hydroxystaurosporine and Cisplatin in Treating Patients With Advanced Malignant Solid Tumors

First Posted Date
2003-01-27
Last Posted Date
2013-07-09
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
30
Registration Number
NCT00012194
Locations
🇺🇸

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States

Combination Chemotherapy in Patients With Advanced Urinary Tract Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-07-03
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
40
Registration Number
NCT00002684
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Bladder Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-07-03
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
30
Registration Number
NCT00003105
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors

First Posted Date
2003-01-27
Last Posted Date
2013-06-26
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
270
Registration Number
NCT00002596
Locations
🇺🇸

FirstHealth Moore Regional Hospital, Pinehurst, North Carolina, United States

🇺🇸

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

🇺🇸

Louis A. Weiss Memorial Hospital, Chicago, Illinois, United States

and more 150 locations

Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-06-14
Lead Sponsor
Children's Oncology Group
Target Recruit Count
277
Registration Number
NCT00003994
Locations
🇺🇸

Children's Oncology Group, Arcadia, California, United States

Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-06-12
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
608
Registration Number
NCT00022191
Locations
🇺🇸

Veterans Affairs Medical Center - Tucson, Tucson, Arizona, United States

🇺🇸

Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, United States

🇺🇸

Louisiana State University Health Sciences Center - Shreveport, Shreveport, Louisiana, United States

and more 231 locations

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Esophagus

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-06-05
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00030862
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

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