Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Gemcitabine Plus Cisplatin in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Is Recurrent or Has Not Responded to Platinum-based Chemotherapy

First Posted Date
2003-01-27
Last Posted Date
2013-05-27
Lead Sponsor
Gynecologic Oncology Group
Registration Number
NCT00006028
Locations
🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, United States

🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

and more 28 locations

Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2020-10-22
Lead Sponsor
Radiation Therapy Oncology Group
Registration Number
NCT00006027
Locations
🇺🇸

Fred Hutchinson Cancer Research Center, Seattle, Washington, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

Community Hospital of Los Gatos, Los Gatos, California, United States

and more 26 locations

Combination Chemotherapy Followed by Radiation Therapy With or Without Paclitaxel in Treating Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-18
Lead Sponsor
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Target Recruit Count
300
Registration Number
NCT00039039
Locations
🇮🇹

Ospedale San Bortolo, Vicenza, Italy

🇮🇹

Ospedale Mariano Santo, Cosenza, Italy

🇮🇹

Ospedale San Martino, Genoa, Italy

and more 34 locations

Combination Chemotherapy in Treating Patients With Advanced Solid Tumors

First Posted Date
2003-01-27
Last Posted Date
2014-02-24
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
13
Registration Number
NCT00046917
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma

First Posted Date
2003-01-27
Last Posted Date
2019-04-25
Lead Sponsor
Children's Hospital of Philadelphia
Target Recruit Count
30
Registration Number
NCT00031590
Locations
🇺🇸

Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto, California, United States

🇺🇸

Winship Cancer Institute of Emory University, Atlanta, Georgia, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Chemotherapy and Radiation Therapy Following Surgery in Treating Patients With Head and Neck Cancer

First Posted Date
2003-01-27
Last Posted Date
2015-11-17
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
70
Registration Number
NCT00011999
Locations
🇺🇸

Albert Einstein Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

and more 231 locations

Combination Chemotherapy in Treating Patients With Stage I, II, or IIIA Non-small Cell Lung Cancer That Has Been Surgically Removed

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-09-20
Lead Sponsor
European Institute of Oncology
Target Recruit Count
750
Registration Number
NCT00003053
Locations
🇮🇹

Ospedale San Filippo Neri, Rome, Italy

🇮🇹

Universita Degli Studi di Bari Policlinico, Bari, Italy

🇮🇹

Ospedale Oncologico A. Businco, Cagliari, Italy

and more 82 locations

Paclitaxel, Cisplatin, and Filgrastim Combined With Radiation Therapy in Treating Patients With Locally Recurrent Head and Neck Cancer

First Posted Date
2003-01-27
Last Posted Date
2015-11-17
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
105
Registration Number
NCT00005087
Locations
🇺🇸

Mount Diablo Medical Center, Concord, California, United States

🇺🇸

Wilkes Barre General Hospital, Wilkes-Barre, Pennsylvania, United States

🇺🇸

Marlene and Stewart Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland, United States

and more 232 locations

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Metastatic Melanoma

First Posted Date
2003-01-27
Last Posted Date
2013-09-05
Lead Sponsor
University of Chicago
Target Recruit Count
46
Registration Number
NCT00004141
Locations
🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

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