Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Gemcitabine, Cisplatin, and Amifostine Following Surgery in Treating Patients With Locally Advanced Bladder Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-09-05
Lead Sponsor
University of Chicago
Target Recruit Count
37
Registration Number
NCT00006105
Locations
🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-26
Lead Sponsor
University College London (UCL) Cancer Institute
Target Recruit Count
600
Registration Number
NCT00025090
Locations
🇬🇧

Cancer Research UK and University College London Cancer Trials Centre, London, England, United Kingdom

🇬🇧

Northwick Park Hospital, Harrow, England, United Kingdom

🇬🇧

Cookridge Hospital, Leeds, England, United Kingdom

and more 10 locations

Chemotherapy and Peripheral Stem Cell Transplant With or Without Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-12
Lead Sponsor
Commissie Voor Klinisch Toegepast Onderzoek
Target Recruit Count
340
Registration Number
NCT00012051
Locations
🇳🇱

Academisch Medisch Centrum at University of Amsterdam, Amsterdam, Netherlands

🇧🇪

U.Z. Gasthuisberg, Leuven, Belgium

🇳🇱

HagaZiekenhuis - Locatie Leyenburg, 's-Gravenhage, Netherlands

and more 14 locations

Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma

Phase 2
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-07
Lead Sponsor
Children's Cancer and Leukaemia Group
Target Recruit Count
260
Registration Number
NCT00025064
Locations
🇬🇧

Birmingham Children's Hospital, Birmingham, England, United Kingdom

🇬🇧

Addenbrooke's Hospital at Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, United Kingdom

🇬🇧

Leeds Cancer Centre at St. James's University Hospital, Leeds, England, United Kingdom

and more 17 locations

Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma

Phase 2
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-07
Lead Sponsor
British Thoracic Society
Registration Number
NCT00030459
Locations
🇬🇧

Medical Research Council Clinical Trials Unit, London, England, United Kingdom

🇬🇧

Leeds Teaching Hospital Trust, Leeds, England, United Kingdom

🇬🇧

Princess Royal Hospital, Hull, England, United Kingdom

and more 6 locations

Chemotherapy and Surgery Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Neuroblastoma

Phase 2
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-07
Lead Sponsor
Children's Cancer and Leukaemia Group
Registration Number
NCT00024193
Locations
🇫🇷

Institut Gustave Roussy, Villejuif, France

Chemotherapy and Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-02
Lead Sponsor
German Society for Pediatric Oncology and Hematology GPOH gGmbH
Registration Number
NCT00017225
Locations
🇩🇪

Carl - Thiem - Klinkum Cottbus, Cottbus, Germany

🇩🇪

Klinikum Lippe - Detmold, Detmold, Germany

🇩🇪

Praxis am Evangelischen Krankenhaus Bethanien, Iserlohn, Germany

and more 85 locations

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Endometrial Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-02
Lead Sponsor
Nordic Society of Gynaecological Oncology - Clinical Trials Unit
Target Recruit Count
400
Registration Number
NCT00005583
Locations
🇬🇧

Centre for Cancer Research and Cell Biology at Belfast City Hospital, Belfast, Northern Ireland, United Kingdom

🇬🇧

Western Infirmary, Glasgow, Scotland, United Kingdom

🇮🇹

Azienda Ospedaliera Di Parma, Parma, Italy

and more 20 locations
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