Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Study of ZG005 in Combination With Etoposide and Cisplatin in Participants With Advanced Neuroendocrine Carcinoma.

First Posted Date
2024-04-18
Last Posted Date
2024-06-14
Lead Sponsor
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Target Recruit Count
93
Registration Number
NCT06372626
Locations
🇨🇳

Chinese PLA General Hospital, Beijing, Beijing, China

The Impact of Neoadjuvant Chemotherapy on Survival Outcomes in Patients With Variant Histologies Bladder Cancer Who Underwent Radical Cystectomy

First Posted Date
2024-04-10
Last Posted Date
2024-04-10
Lead Sponsor
Ankara Etlik City Hospital
Target Recruit Count
221
Registration Number
NCT06358599
Locations
🇹🇷

Ankara Etlik City Hospital, Ankara, Turkey

Hypofractionated Radiochemotherapy

First Posted Date
2024-03-26
Last Posted Date
2024-12-11
Lead Sponsor
Denise Fabian
Target Recruit Count
20
Registration Number
NCT06331468
Locations
🇺🇸

Markey Cancer Center, Lexington, Kentucky, United States

SBRT and LDRT Combined With PD-1 Antibody and Chemotherapy in r/m Nasopharyngeal Carcinoma

First Posted Date
2024-03-21
Last Posted Date
2024-08-20
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
148
Registration Number
NCT06323239
Locations
🇨🇳

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

First Posted Date
2024-03-15
Last Posted Date
2024-12-05
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
780
Registration Number
NCT06312137
Locations
🇨🇳

Zhongshan Hospital of Fudan University ( Site 1325), Shangai, Shanghai, China

🇫🇷

Groupe hospitalier Paris saint Joseph. ( Site 1807), Paris, Ile-de-France, France

🇫🇷

Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne-ONCOLOGY ( Site 1810), Clermont-Ferrand, Puy-de-Dome, France

and more 124 locations

GAMEC-II, Risk-adapted Protocol for Relapsed Germ Cell Tumours (GCT)

First Posted Date
2024-03-13
Last Posted Date
2024-03-13
Lead Sponsor
Queen Mary University of London
Target Recruit Count
36
Registration Number
NCT06309732
Locations
🇬🇧

Barts and the London NHS Trust, London, United Kingdom

The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients.

First Posted Date
2024-03-06
Last Posted Date
2024-03-06
Lead Sponsor
Odense University Hospital
Target Recruit Count
264
Registration Number
NCT06295094
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇫🇷

University Hospital Lille, Lille, France

🇩🇪

Charité, University of Berlin, Berlin, Germany

and more 2 locations
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