MedPath

NT-201

Generic Name
NT-201

A Study of NT 201 in the Treatment of Enlarged Pores and Excessive Sebum Production in the Face

Phase 1
Completed
Conditions
Enlarged Pores
Sebum Production
Interventions
Drug: Placebo
First Posted Date
2023-03-24
Last Posted Date
2024-08-23
Lead Sponsor
Merz North America, Inc.
Target Recruit Count
31
Registration Number
NCT05784363
Locations
🇺🇸

Merz Investigation Site #0010473, Los Angeles, California, United States

🇺🇸

Merz Investigation Site #001097, Nashville, Tennessee, United States

🇺🇸

Merz Investigation Site #0010101, Coral Gables, Florida, United States

A Study of NT 201 Doses in the Treatment of Platysma Prominence

Phase 2
Completed
Conditions
Platysma Prominence
Interventions
Drug: NT 201 Placebo
First Posted Date
2023-03-17
Last Posted Date
2024-10-21
Lead Sponsor
Merz Aesthetics GmbH
Target Recruit Count
73
Registration Number
NCT05773053
Locations
🇺🇸

Merz Investigation Site #0010170, Washington, District of Columbia, United States

🇺🇸

Merz Investigation Site #0010470, Coral Gables, Florida, United States

🇺🇸

Merz Investigation Site #0010405, New York, New York, United States

and more 4 locations

A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm

Phase 2
Completed
Conditions
Essential Tremor of the Upper Limb
Interventions
Drug: Placebo
First Posted Date
2021-02-23
Last Posted Date
2024-04-22
Lead Sponsor
Merz Pharmaceuticals GmbH
Target Recruit Count
78
Registration Number
NCT04766723
Locations
🇺🇸

Mount Sinai Medical Center, Merz Investigational Site #0010191, New York, New York, United States

🇺🇸

Medstar Georgetown Neurology, Merz Investigational Site #0010231, McLean, Virginia, United States

🇨🇦

London Health Sciences Centre, Merz Investigational Site #0010087, London, Ontario, Canada

and more 11 locations

Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Crows Feet) in Subjects With Moderate to Severe Upper Facial Lines

Phase 3
Completed
Conditions
Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)
Interventions
Drug: Placebo
First Posted Date
2020-11-09
Last Posted Date
2024-08-06
Lead Sponsor
Merz North America, Inc.
Target Recruit Count
368
Registration Number
NCT04622254
Locations
🇩🇪

Merz Investigational Site, Wuppertal, Germany

Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Lateral Canthal Lines) in Subjects With Moderate to Severe Upper Facial Lines

Phase 3
Completed
Conditions
Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)
Interventions
Drug: Placebo
First Posted Date
2020-10-20
Last Posted Date
2024-05-08
Lead Sponsor
Merz North America, Inc.
Target Recruit Count
362
Registration Number
NCT04594213
Locations
🇺🇸

Merz Investigational Site, Nashville, Tennessee, United States

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

Phase 3
Active, not recruiting
Conditions
Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury
Interventions
Drug: Placebo
First Posted Date
2019-06-20
Last Posted Date
2025-05-15
Lead Sponsor
Merz Pharmaceuticals GmbH
Target Recruit Count
603
Registration Number
NCT03992404
Locations
🇧🇪

CHU Brugmann Neurology; Merz investigational site #0320015, Brussel, Belgium

🇺🇦

Lviv regional clinical hospital; Merz investigational site # 3800020, Lviv, Ukraine

🇺🇸

Physical Medicine and Rehabilitation at University of Alabama at Birmingham; Merz investigational site #0010479, Birmingham, Alabama, United States

and more 68 locations

Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown Lines

Phase 2
Completed
Conditions
Moderate to Severe Glabellar Frown Lines
Interventions
First Posted Date
2019-01-16
Last Posted Date
2023-11-15
Lead Sponsor
Merz Aesthetics GmbH
Target Recruit Count
241
Registration Number
NCT03806933
Locations
🇺🇸

Medical Associates Inc., Merz Investigational Site #0010435, Newport Beach, California, United States

🇩🇪

Skin & Laser Center, Merz Investigational Site #0490362, Potsdam, Germany

🇺🇸

Clinical Testing of Beverly Hills, Merz Investigational Site #0010395, Encino, California, United States

and more 6 locations

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability

Phase 3
Completed
Conditions
Chronic Troublesome Sialorrhea
Stroke
Traumatic Brain Injury
Intellectual Disability
Cerebral Palsy
Interventions
Drug: NT 201 Placebo
First Posted Date
2014-10-21
Last Posted Date
2021-08-10
Lead Sponsor
Merz Pharmaceuticals GmbH
Target Recruit Count
256
Registration Number
NCT02270736
Locations
🇬🇪

Merz Investigational Site #9950001, Tbilisi, Georgia

🇺🇦

Merz Investigational Site #3800001, Dnipropetrovsk, Ukraine

🇺🇦

Merz Investigational site #3800003, Odesa, Ukraine

and more 28 locations

Safety and Efficacy of NT 201, Free of Complexing Proteins, in the Treatment of Glabellar Frown Lines

Phase 3
Completed
Conditions
Healthy
First Posted Date
2008-06-10
Last Posted Date
2012-10-30
Lead Sponsor
Merz Pharmaceuticals GmbH
Target Recruit Count
108
Registration Number
NCT00694148
Locations
🇩🇪

Dr. Matthias Imhof, Medico Palais Bad Soden, Bad Soden, Hessen, Germany

Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia

Phase 4
Completed
Conditions
Cervical Dystonia
Interventions
First Posted Date
2007-10-10
Last Posted Date
2013-06-04
Lead Sponsor
Merz Pharmaceuticals GmbH
Target Recruit Count
82
Registration Number
NCT00541905
Locations
🇩🇪

Medizinische Hochschule Hannover (LKP), Hannover, Germany

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